Publication details

 

On Parameter Synthesis by Parallel Model Checking

Basic information
Original title:On Parameter Synthesis by Parallel Model Checking
Authors:Jiří Barnat, Luboš Brim, Adam Krejčí, Adam Streck, David Šafránek, Martin Vejnár, Tomáš Vejpustek
Further information
Citation:BARNAT, Jiří - BRIM, Luboš - KREJČÍ, Adam - STRECK, Adam - ŠAFRÁNEK, David - VEJNÁR, Martin - VEJPUSTEK, Tomáš. On Parameter Synthesis by Parallel Model Checking. IEEE/ACM Transactions on Computational Biology and Bioinformatics, Los Alamitos, IEEE Computer Society. ISSN 1545-5963, 2012, vol. 9, no. 3, pp. 693-705.
Original language:English
Field:Informatika
Type:Article in Periodical
Keywords:biological networks; parallel model checking; dynamical systems; parameter synthesis; systems biology

An important problem in current computational systems biology is to analyse models of biological systems dynamics under parameter uncertainty. This paper presents a novel algorithm for parameter synthesis based on parallel model checking. The algorithm is conceptually universal with respect to the modelling approach employed. We introduce the algorithm, show its scalability, and examine its applicability on several biological models.

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