RNDr. Pavel Krejčí, Ph.D.

2010

• Nf449 is a novel inhibitor of fibroblast growth factor receptor 3 (fgfr3) signaling active in chondrocytes and multiple myeloma cells

  KREJČÍ Pavel MURAKAMI Shunichi PROCHÁZKOVÁ Jiřina TRANTÍREK Lukáš CHLEBOVÁ Katarína OUYANG Zhufeng AKLIAN Anie SMUTNÝ Jiří BRYJA Vítězslav KOZUBÍK Alois WILCOX Wiliam R.

  Article in Periodical

  J. Biol. Chem., year: 2010, volume: 285, edition: 27, DOI

2009

• FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway

  MATSUSHITA Takehiko WILCOX William YUK YU Chan KAWANAMI Aya BÜKÜLMEZ Hülya BALMES Gener KREJČÍ Pavel MEKIKIAN Pertchoui B OTANI Kazuyuki YAMAURA Isakichi WARMAN Matthew L. GIVOL David MURAKAMI Shunichi

  Article in Periodical

  Human Molecular Genetics, year: 2009, volume: 18, edition: 2

• Fibroblast growth factor inhibits interferon gama-STAT1 and interleukin 6-STAT3 signaling in chondrocytes

  KREJČÍ Pavel PROCHÁZKOVÁ Jiřina BRYJA Vítězslav JELÍNKOVÁ Petra PEJCHALOVÁ Kateřina KOZUBÍK Alois TOMPSON Leslie Michels WILCOX William R.

  Article in Periodical

  Cellular Signalling, year: 2009, volume: 21, edition: 1, DOI

• High molecular weight FGF2: the biology of a nuclear growth factor

  CHLEBOVÁ Katarína BRYJA Vítězslav DVOŘÁK Petr KOZUBÍK Alois WILCOX W.R. KREJČÍ Pavel

  Article in Periodical

  Cellular and molecular life sciences : CMLS, year: 2009, volume: 66, edition: 2, DOI

• Molecular pathology of the fibroblast growth factor family.

  KREJČÍ Pavel PROCHÁZKOVÁ Jiřina BRYJA Vítězslav KOZUBÍK Alois WILCOX William

  Article in Periodical

  Human Mutation, year: 2009, volume: 30, edition: 9, DOI

2008

• A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells

  SALAZAR Lisa KASHIWADA Tamara KREJČÍ Pavel MUCHOWSKI Paul DONOGHUE Daniel WILCOX William THOMPSON Leslie Michels

  Article in Periodical

  HUMAN MOLECULAR GENETICS, year: 2008, volume: 18, edition: 11

• Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage

  KREJČÍ Pavel SALAZAR Lisa KASHIWADA Tamara A. CHLEBOVÁ Katarína SALAŠOVÁ Alena THOMPSON Leslie Michels BRYJA Vítězslav KOZUBÍK Alois WILCOX William R.

  Article in Periodical

  PLoS ONE., year: 2008, volume: 3, edition: 12

• STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes

  KREJČÍ Pavel SALAZAR Lisa GOODRIDGE Helen KASHIWADA Tamara SCHIBLER Matthew JELÍNKOVÁ Petra THOMPSON, Leslie Michels WILCOX William

  Article in Periodical

  JOURNAL OF CELL SCIENCE, year: 2008, volume: 121, edition: 3

2007

• C-natriuretic peptide: an important regulator of cartilage.

  PEJCHALOVÁ Kateřina KREJČÍ Pavel WILCOX William R.

  Article in Periodical

  Molecular Genetics and Metabolism, year: 2007, volume: 92, edition: 3, DOI

• Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligandsexpressed in human fetal growth plate cartilage.

  KREJČÍ Pavel KRAKOW D. MEKIKIAN P.B. WILCOX William R.

  Article in Periodical

  Pediatric Research, year: 2007, volume: 61, edition: 3, DOI