doc. Mgr. Lumír Krejčí, Ph.D.

2017

• Pyrazolotriazines as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit, Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: European Patent Office, state: Germany, patent's number: EP2957562, year: 2017

• RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

  DI MARCO Stefano HAŠANOVÁ Zdenka KANAGARAJ Radhakrishnan CHAPPIDI Nagaraja ALTMANNOVÁ Veronika MENON Shruti SEDLÁČKOVÁ Hana LANGHOFF Jana SURENDRANATH Kalpana HÜHN Daniela BHOWMICK Rahul MARINI PALOMEQUE María Victoria FERRARI Stefano HICKSON Ian D. KREJČÍ Lumír JANSCAK Pavel

  Article in Periodical

  Molecular Cell, year: 2017, volume: 66, edition: 5, DOI

• Role of PCNA and RFC in promoting Mus81-complex activity

  SISÁKOVÁ Alexandra ALTMANNOVÁ Veronika ŠEBESTA Marek KREJČÍ Lumír

  Article in Periodical

  BMC BIOLOGY, year: 2017, volume: 15, edition: 90, DOI

• Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

  KOLINJIVADI A.M. SANNINO V. DE ANTONI A. MOVSESJAN Karina KILKENNY M. TECHER H. BALDI G. SHEN R. CICCIA A. PELLEGRINI L. KREJČÍ Lumír COSTANZO V.

  Article in Periodical

  Molecular Cell, year: 2017, volume: 67, edition: 5, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI

• Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci

  VASIANOVICH Yulia ALTMANNOVÁ Veronika KOTENKO Oleksii NEWTON Matthew D. KREJČÍ Lumír MAKOVETS Svetlana

  Article in Periodical

  EMBO Journal, year: 2017, volume: 36, edition: 2, DOI

2016

• A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling

  TAYLOR Martin R.G. ŠPÍREK Mário MA Chu Jian CARZANIGA Raffaella TAKAKI Tohru COLLINSON Lucy M. GREENE Eric C. KREJČÍ Lumír BOULTON Simon J.

  Article in Periodical

  Molecular Cell, year: 2016, volume: 64, edition: 5, DOI

• Cancer TARGETases: DSB Repair as a Pharmacological Target

  SAMADDER Pounami AITHAL Rakesh BELÁŇ Ondrej KREJČÍ Lumír

  Article in Periodical

  Pharmacology & Therapeutics, year: 2016, volume: 161, edition: "May", DOI

• DNA, the central molecule of aging

  LÉNÁRT Peter KREJČÍ Lumír

  Article in Periodical

  Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis, year: 2016, volume: 786, edition: "April", DOI

• DSB formation by Spo11 protein requires interaction with Mre11

  AITHAL Rakesh NANGALIA Kuldeep KLEIN Franz KREJČÍ Lumír

  Appeared in Conference without Proceedings

  Year: 2016, type: Appeared in Conference without Proceedings