RNDr. Martin Toul, Ph.D.

2024

• Azobenzene-Based Photoswitchable Substrates for Advanced Mechanistic Studies of Model Haloalkane Dehalogenase Enzyme Family

  SLÁNSKÁ Michaela ŠTACKOVÁ Lenka MARQUES Sérgio Manuel ŠTACKO Peter MARTÍNEK Marek JÍLEK Luboš TOUL Martin DAMBORSKÝ Jiří BEDNÁŘ David KLÁN Petr PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2024, volume: 14, edition: 15, DOI

2023

• Catalytic mechanism for Renilla-type luciferases

  SMITH Andrea TOUL Martin PLUSKAL Daniel BAATALLAH Racha GAGNOT Glwadys RANGEL PAMPLONA PIZARRO PINTO José Gaspar SANTANA Vinicius T. T. STUCHLÁ Markéta NEUGEBAUER Petr CHAIYEN Pimchai DAMBORSKÝ Jiří BEDNÁŘ David JANIN Yves L. L. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Nature Catalysis, year: 2023, volume: 6, edition: 1, DOI

• Identification, characterization, and engineering of glycosylation in thrombolytics

  TOUL Martin SLONKOVÁ Veronika MIČAN Jan URMINSKÝ Adam Paulin TOMKOVA Maria SEDLÁK Erik BEDNÁŘ David DAMBORSKÝ Jiří HERNYCHOVÁ Lenka PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI

• Illuminating the mechanism and allosteric behavior of NanoLuc luciferase

  NEMERGUT Michal PLUSKAL Daniel HORÁČKOVÁ Jana ŠUSTROVÁ Tereza TULIS Jan BÁRTA Tomáš BAATALLAH Racha GAGNOT Glwadys NOVÁKOVÁ Veronika MAJEROVÁ Marika SEDLÁČKOVÁ Karolina MARQUES Sérgio Manuel TOUL Martin DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David JANIN Yves L. MAREK Martin

  Article in Periodical

  Nature Communications, year: 2023, volume: 14, edition: 1, DOI

• Poměr plazminogen/plazmin jako ukazatel bezpečnosti trombolytické léčby

  BRHELOVÁ Eliška SLONKOVÁ Veronika TOUL Martin KOVÁŘ David THALEROVÁ Sandra HLOŽKOVÁ Jana SCHEER Peter AKSU Ahmet Davut OPATŘILOVÁ Radka PROKOP Zbyněk DAMBORSKÝ Jiří MIKULÍK Robert

  Conference abstract

  Year: 2023, type: Conference abstract

2022

• Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin

  NIKITIN Dmitri MIČAN Jan TOUL Martin BEDNÁŘ David PEŠKOVÁ Michaela KITTOVÁ Patrícia THALEROVÁ Sandra VÍTEČEK Jan DAMBORSKÝ Jiří MIKULÍK Robert FLEISHMAN Sarel J. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2022, volume: 20, edition: May 2022, DOI

• Extended Mechanism of the Plasminogen Activator Staphylokinase Revealed by Global Kinetic Analysis: 1000-fold Higher Catalytic Activity than That of Clinically Used Alteplase

  TOUL Martin NIKITIN Dmitri MAREK Martin DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2022, volume: 12, edition: 7, DOI

• Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase

  TOUL Martin MIČAN Jan SLONKOVÁ Veronika NIKITIN Dmitri MAREK Martin BEDNÁŘ David DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  Stroke, year: 2022, volume: 53, edition: 10, DOI

• IMPACT OF ADMINISTRATION METHOD OF THROMBOLYTICS ON THEIR THROMBOLYTIC EFFECTS

  DAVUT AKSU Ahmet HLOŽKOVÁ Jana SCHEER Peter BRHELOVÁ Eliška MIČAN Jan TOUL Martin DAMBORSKÝ Jiří KAŠPÁREK Petr DOLAŽALOVÁ Jana MIKULÍK Robert

  Appeared in Conference without Proceedings

  Year: 2022, type: Appeared in Conference without Proceedings

2021

• Development and Testing of Thrombolytics in Stroke

  NIKITIN Dmitri CHOI Seungbum MIČAN Jan TOUL Martin RYU Wi-Sun DAMBORSKÝ Jiří MIKULÍK Robert KIM Dong-Eog

  Article in Periodical

  JOURNAL OF STROKE, year: 2021, volume: 23, edition: 1, DOI