Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2001
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Vliv metamfetaminu na aktivitu CYP2D1 na modelu perfundovaných jater u samců potkana Wistar albino
45. Studentská vědecká konference Lékařské fakulty MU. Sborník abstrakt., year: 2001
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Vliv metamfetaminu na aktivitu P-450 na modelu perfundovaných jater u potkanů Wistar albino
In Kongres MEFA 2001; Sborník abstrakt, year: 2001
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Vliv tiagabinu, citalopramu a valproátu na lokomočě pátrací chování myší ve vztahu k jejich potenciální antidepresivní aktivitě
Československá fyziologie, year: 2001, volume: 50, edition: 4
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Vliv změn 5-HT1A a 5-HT1B receptorové aktivity na lokomočně-pátrací chování potkanů
Psychiatrie, year: 2001, volume: 5, edition: Suppl. 2
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Využití počítačové analýzy lokomoční a pátrací aktivity myší k možné predikci antidepresivních účinků farmak
Psychiatrie, year: 2001, volume: 5, edition: Suppl. 1
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Vztah mezi EM a PM CYP 2D6 ve výskytu sexuálních dysfunkcí
Psychiatrie, year: 2001, volume: 5, edition: Suppl. 2
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Změny aktivity CYP2D u potkanů medikovaných návykovými látkami.
Psychiatrie, year: 2001, volume: 5, edition: Suppl. 1
2000
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5-HT1A/1B Receptor Function Involvement in Methamphetamine I.V. Self-administration in Rats
A Serotonin Club/Brain Research Bulletin - Serotonin:From the Molecule to the Clinic, year: 2000
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A SEEG study of motor preparation and activity in cortex,thalamus and basal ganglia.
Clinical Neurophysiology, year: 2000, volume: 111, edition: 1
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Acellular nerve graft re-seeded by Schwann cells migrating from the nerve stump can stimulate spinal motoneurons for functional reinnervation of the rat muscle
Ann. Anat., year: 2000, volume: 182, edition: 1