Publication details
Fixní kombinační léčba hypertenze
| Title in English | Fixed-dose combination therapy for hypertension |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Kardiologická revue - Interní medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | hypertension; fixed-dose combination; triple combination |
| Description | We present an overview of current opinions on the position of fi xed-dose combinations in the treatment of hypertension in line with the ESH/ ESC and the Czech Society for Hypertension guidelines of 2013. The most frequently recommended double combinations are a renin angiotensin system inhibitor (ACE-I or sartan) plus a calcium antagonist, a renin angiotensin system inhibitor plus a diuretic, or a calcium antagonist plus a diuretic. A fi xed-dose combination of an ACE inhibitor (perindopril), a calcium channel blocker (amlodipine) and a diuretic (indapamide) was introduced in the Czech market in 2014. The main advantage of fi xed combinations is improved patient compliance, leading to a better control of hypertension. A triple combination is required for good control of hypertension in about one third of patients. |