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Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison

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GOFUS Jan VOJACEK Jan KARALKO Mikita ZACEK Pavel KOLESAR Adrian TOPORCER Tomas URBAN Martin GLAC Filip CERNY Stepan HOMOLA Pavel HLUBOCKY Jaroslav SLAUTIN Andrey FILA Petr ŽÁKOVÁ Daniela ŠTĚRBA Jan RASHID Hiwad VAN LINDEN Arnaud HOLUBEC Tomas

Rok publikování 2024
Druh Článek v odborném periodiku
Časopis / Zdroj EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://academic.oup.com/ejcts/article/66/2/ezae234/7727652?login=true
Doi http://dx.doi.org/10.1093/ejcts/ezae234
Klíčová slova Aortic valve repair; Valve-sparing root replacement; Aortic root aneurysm; Aortic regurgitation; Propensity-score matching
Popis OBJECTIVES: Both aortic root remodelling and aortic valve (AV) reimplantation have been used for valve-sparing root replacement in patients with aortic root aneurysm with or without aortic regurgitation. There is no clear evidence to support one technique over the another. This study aimed to compare remodelling with basal ring annuloplasty versus reimplantation on a multicentre level with the use of propensity-score matching. METHODS: This was a retrospective international multicentre study of patients undergoing remodelling or reimplantation between 2010 and 2021. Twenty-three preoperative covariates (including root dimensions and valve characteristics) were used for propensity-score matching. Perioperative outcomes were analysed along with longer-term freedom from AV reoperation/reintervention and other major valve-related events. RESULTS: Throughout the study period, 297 patients underwent remodelling and 281 had reimplantation. Using propensity-score matching, 112 pairs were selected and further compared. We did not find a statistically significant difference in perioperative outcomes between the matched groups. Patients after remodelling had significantly higher reintervention risk than after reimplantation over the median follow-up of 6 years (P = 0.016). The remodelling technique (P = 0.02), need for decalcification (P = 0.03) and degree of immediate postoperative AV regurgitation (P < 0.001) were defined as independent risk factors for later AV reintervention. After exclusion of patients with worse than mild AV regurgitation immediately after repair, both techniques functioned comparably (P = 0.089). CONCLUSIONS: AV reimplantation was associated with better valve function in longer-term postoperatively than remodelling. If optimal immediate repair outcome was achieved, both techniques provided comparable AV function.

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