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Method of detoxication of yperite by using haloalkane dehalogenases

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PROKOP Zbyněk DAMBORSKÝ Jiří OPLUŠTIL F. JESENSKÁ Andrea NAGATA Yuji

Rok publikování 2012
Druh Patent
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Vydavatel
Stát vydání Kanada
Číslo patentu CA 2610024
Popis Patent granted in Canada "Method of detoxication of yperite by using haloalkane dehalogenases".The method of detoxification of yperite by the use of haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contain at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are DhaA from Rhodococcus rhodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66 or LinB from Sphingomonas paucimobilis UT26. Decontamination is utilized for detoxification of yperite from the surfaces of instrumentality, constructional objects, the people’s or animal’s skin and elements of environment, when yperite is exposed to the action of decontamination composition at +10 C to +70 C, preferably at +40 C and pH = 4 to 12.
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