Informace o publikaci
Sequence-dependent separation of trinucleotides by ion-interaction reversed-phase liquid chromatography A structure-retention study assisted by soft-modelling and molecular dynamics
| Autoři | |
|---|---|
| Rok publikování | 2016 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Journal of Chromatography A |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | supplementary data |
| Doi | http://dx.doi.org/10.1016/j.chroma.2016.09.060 |
| Obor | Analytická chemie, separace |
| Klíčová slova | Sequence-dependent separation; Ion-interaction reversed-phase liquid chromatography; Trinucleotides; Oligonucleotide sequence isomers; QSRR; Molecular dynamics |
| Přiložené soubory | |
| Popis | Ultrashort oligonucleotides show consistent sequence-dependent separation behaviour, described via soft-modelling and molecular dynamics. Important factors determining this phenomenon were identified to be solvent accessible surface areas and electrostatic work of molecule transfer from vacuum into solvent, representing physico-chemical properties of the studied molecules. |
| Související projekty: |