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Identifying patients at high risk of colonic diverticular haemorrhage

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ADAMOVÁ Zuzana SLOVÁČEK Radim SANKOT Jaroslav VLČEK Petr

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Surgical Chronicles
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Chirurgie včetně transplantologie
Klíčová slova diverticular disease; haemorrhage; risk factors; hypertension; ischemic heart disease; age
Popis Aim of the study: Diverticular hemorrhage is a common cause of lower gastrointestinal bleeding, but studies about risk factors for colonic diverticular hemorrhage are limited, most of them are dedicated to Asian population. Our aim was to identify risk factors for diverticular bleeding in westernized population. Material and Methods: This is a retrospective study. There were included 333 consecutive patients, treated for symptomatic diverticular disease between January 2000 and December 2011. Seventy-four (22 %) had signs of diverticular bleeding. The influence of comorbidities (overweight, hypertension, ischemic cardiac disease, atrial fibrillation, renal failure, gastroduodenal disease), nicotine abuse and medication (anticoagulant drugs, aspirin) was evaluated. To determine the risk factors for colonic diverticular bleeding statistical analysis were performed using Mann–Whitney U test and Fisher’s exact test. Results: There was no difference between patients with diverticular hemorrhage and those with non bleeding symptomatic diverticulosis regarding gender ratio. Bleeding patients were older (p<0,00001). Hypertension (p= 0,00001), ischemic heart disease (p=0,04), gastroduodenal disease (p<0,00001) and use of aspirin(p=0,007) were significant risk factors for diverticular bleeding. Conclusions: Age, hypertension, ischemic heart disease, gastroduodenal disease and use of aspirin increase significantly the risk of diverticular hemorrhage.

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