Informace o publikaci
Preparation and Photosynthesis-Inhibiting Activity of 1-[(2-Nitrophenyl) carbamoyl] naphthalen-2-yl Alkylcarbamates
| Autoři | |
|---|---|
| Rok publikování | 2016 |
| Druh | Článek ve sborníku |
| Konference | 20TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY (ECSOC) |
| Citace | |
| Doi | http://dx.doi.org/10.3390/ecsoc-20-b004 |
| Klíčová slova | Alkylcarbamates; Hydroxynaphthalene-carboxamides; PET inhibition; Spinach chloroplasts; Structure-activity relationships |
| Popis | In this study, a series of eight 1-[(2-nitrophenyl) carbamoyl] naphthalen-2-yl alkylcarbamates was prepared and characterized. The discussed compounds were prepared by microwave-assisted and conventional synthesis. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low; the corresponding IC50 values ranged from 0.233 to 0.487 mmol/L and the highest activity within the series of compounds was observed for 1-[(2-nitrophenyl) carbamoyl] naphthalen-2-yl pentylcarbamate. The compounds were found to inhibit PET in photosystem II. |