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Actin cytoskeleton in human fungal pathogen Cryptococcus neoformans

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KOPECKÁ Marie TAKEO Kanji GABRIEL Miroslav SVOBODA Augustin

Rok publikování 1999
Druh Článek ve sborníku
Konference VII. Cytoskeletální klub
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Mikrobiologie, virologie
Klíčová slova actin; fungi; human pathogen
Popis Human fungal pathogen Cryptococus neoformans was examined by rhodamine-phalloidin and DAPI staining to identify actin cytoskeleton structures and nuclei. Saccharomyces and Schizosaccharomyces were used as controls.Spherical cells of C. neoformans revealed dense intracellular network of actin microfilament cables, oriented to developing bud. ASctin patches were accumulated at area of the growing bud, but also present in mother cells. Actin ring appeared in the neck region between mother and daughter cell. C. neoformans has well developed yeast actin cytoskeleton with specific features.
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