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The changes of biological markers and treatment efficacy in schizophrenia/Abstract/

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ČEŠKOVÁ Eva DRYBČÁK Pavel HROBAŘ Petr LORENC Miroslav PROCHÁZKOVÁ Hana ŠPAČEK Josef

Rok publikování 2001
Druh Článek v odborném periodiku
Časopis / Zdroj Progres in Psychopharmacology Biological Psychiatry"
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Psychiatrie, sexuologie
Klíčová slova biological markers; schizophrenia; outcome; neuropsychology
Popis In a group of schizophrenic patients , the effect and selected parameters of biological markers were evaluated during the index hospitalisation in the acute phase of schizophrenia (n=30) and then after one year of ambulatory treatment. After one year an average tendency towards clinical improvement and positive shifts in some objective parameters were found. The comparison between the successfully and the unsuccessfuly treated patients after the period of one year confirmed that the negative symptomatology and some easily available, in terms of time and resources undemanding parameters of biological markers may be important also for the long-term prognosis and the efficacy of maintenance treatment.
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