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Informace o publikaci
Western blot determination of IgG avidity in primary and secondary syphilis.
Autoři | |
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Rok publikování | 2001 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Scripta medica (Brno) |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Mikrobiologie, virologie |
Klíčová slova | low-avidity IgG; syphilis; Western blot |
Popis | IgG avidity to p15.5 kD, p17 kD, and p47 kD antigens of Treponema pallidum was analysed by a new avidity assay termed avidity Western blot. Group I consisted of sera from 27 patients with primary and secondary syphilis, group II comprised 10 subjects with latent syphilis. Low-avidity antibodies were directed against the p17 kD and p47 kD antigens in group I and against the p47 kD antigen in group II. No low-avidity IgG antibodies were detected by ELISA, a routine method for avidity assessment. |