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Induced differentiation and apoptosis in HL-60 cell line modulated by caffeic acid treatment
Autoři | |
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Rok publikování | 2002 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | |
Popis | The aim of presented study was to investigate possible effect of caffeic acid (CA) in combination with known differentiating agents, all-trans retinoic acid (ATRA) or dimethylsulfoxide (DMSO) respectively, on the HL-60 human myeloid leukemia cell line. Treatment of the HL-60 cells by CA in combination with known differentiation inductors ATRA and DMSO leads to the reduction of cell viability and increased frequency of apoptosis. |
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