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Informace o publikaci
Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates
Název česky | Syntéza a reakce methyl-2-[3-(2-fenylchinazolin-4-yl)thioureido]alkanoátů |
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Autoři | |
Rok publikování | 2007 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | ARKIVOC |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Organická chemie |
Klíčová slova | Non-nucleoside RT inhibitors; quinazoline; thioureas; amino acids; imidoyl isothiocyanate; Domino-reaction; intramolecular cyclization |
Popis | Methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates bearing an amino acid ester residue were prepared by a novel three step sequential reaction of N-(2-cyanophenyl)benzimidoyl isothioyanate with amino acid methyl ester hydrochlorides. Some chemoselective reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates with alkyl halides were studied. |
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