Informace o publikaci

Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance

Autoři

DUBSKÁ Lenka PILÁTOVÁ Kateřina DOLEJSKÁ Monika BORTLÍČEK Zbyněk FROSTOVÁ Tereza LITERÁK Ivan VALÍK Dalibor

Rok publikování 2011
Druh Článek v odborném periodiku
Časopis / Zdroj Anaerobe
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1016/j.anaerobe.2011.05.008
Obor Mikrobiologie, virologie
Klíčová slova SELDI-TOF MS; Phenotyping; Bacteria identification
Popis Based on experiments with 10 defined strains of Escherichia coli, we present a new method for bacterial phenotyping using SELDI-TOF mass spectrometry. Changes in bacterial protein profiles in the context of the time of cultivation and the antibiotic environment were minimal. Proteom subprofiling may further distinguish between strains with specific susceptibility to antimicrobials. Mass spec-based methods may become common in the future of bacterial pathogen identification in clinical microbiology diagnostics.

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.

Další info