POSTDOC POSITION in biomedical research: Role of DNA repair proteins in metabolism of G4 structures

Medical Faculty of Masaryk University, Brno, Czech Republic invites excellent scientists to apply for a two-year

POSTDOC POSITION in biomedical research: Role of DNA repair proteins in metabolism of G4 structures

A postdoc position is available at Lumír Krejčí Research Group, Laboratory of Recombination and DNA Repair, Department of Biology. The laboratory is devoted to fundamental studies in processing of stalled replication forks and how this process contributes to genome instability and disease development. Examples of the recently studied problems in our lab include (1) role of homologous recombination proteins in processing stalled replication forks, (2) role of phase separation in genome maintenance, (3) characterisation of Rothmund-Thomson helicase, (4) role of G4 structures in genome stability, and (5) identification and optimisation of novel nuclease inhibitors for improved therapy. For more details, see: https://www2.med.muni.cz/lord/ or contact Lumir Krejci: lkrejci@chemi.muni.cz

The successful candidate should:

• Hold a Ph.D. in molecular biology, biochemistry or similar field or its equivalent, awarded within the past 7 years, AND have worked in research for at least 2 years of work, within the last 3 years, outside the Czech Republic (with a workload equivalent to at least 0.5 full-time employment)
• Alternatively, hold a Ph.D. diploma (or equivalent) from an international institution awarded within the past 3 years
• Demonstrate a publication record that includes a minimum of three research outputs (articles) within the past three years, surpassing the field's median standards, with at least two of them ranked in Q1 according to Web of Science.

Specific qualifications include:

• Exhibit a genuine passion for scientific exploration and a deep-seated curiosity
• Possessing a robust foundation in genetics, molecular biology, biochemistry, and biophysics will be greatly advantageous
• Display exceptional communication abilities and a collaborative spirit
• Demonstrate strong organizational skills
• Show independence and enthusiasm

Include these in your application:

• A comprehensive CV detailing your publication history
• A copy of your PhD diploma
• Contact information for two referees who can provide insights into your qualifications
• A brief but substantive description of your research focus and the specific topic you intend to investigate. Justify the relevance of this research within the field
• Submission of documents validating that you have accumulated a minimum of two full years of work experience outside the Czech Republic within the past three years, and/or proof of a Ph.D. diploma from a foreign institution.
   

We offer:

• An exceptionally competitive salary (2.500 - 3.200 groos EUR/month), commensurate with the applicant's skills and proficiency.
• Access to Core Facilities and state-of-the-art facilities, including advanced imaging and sequencing technologies
• An enticing position within a rapidly evolving university precinct.
• A range of diverse and stimulating responsibilities within an outstanding research environment.
• An initial two-year appointment.
• The opportunity to collaborate with a professional team in a comfortable work environment.
• Interaction with renowned scientists within an inspiring, globally-connected setting.
• A dedicated welcome service tailored to the needs of the successful candidate and their family.

Anticipated start date: The position is available from April 2025 or upon agreement
The submission deadline is 31st January 2025

Please submit e-application.

For more information, please contact Martina Vráblíková by e-mail vrablikova@med.muni.cz.
The assessment of applications will begin promptly upon the deadline's closure. Candidates who make the shortlist will receive invitations for interviews within one month following the application deadline.
 

Further information about:

• Medical Faculty is available at https://www.med.muni.cz/en
• Masaryk University is available at https://www.muni.cz/en
• Brno is available at https://www.gotobrno.cz/en/