Mgr. Dalibor Blažek, Ph.D.

2018

• CDK12 kinase activity controls G1/S progression by regulating optimal transcription of core DNA replication genes

  CHIRACKAL MANAVALAN Anil Paul PILAŘOVÁ Květa KLUGE M. BARTHOLOMEEUSEN Koen OPPELT Jan KHIRSARIYA PrashantKumar PARUCH Kamil KREJČÍ Lumír FRIEDEL C. BLAŽEK Dalibor

  Conference abstract

  Year: 2018, type: Conference abstract

2016

• Structural and Functional Analysis of the Cdk13/Cyclin K Complex

  GREIFENBERG Ann Katrin HÖNIG Dana PILAŘOVÁ Květa DÜSTER Robert BARTHOLOMEEUSEN Koen BOSKEN Christian A. ANAND Kanchan BLAŽEK Dalibor GEYER Matthias

  Article in Periodical

  Cell Reports, year: 2016, volume: 14, edition: 2, DOI

• The CD8+cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+cells

  BLAŽEK Dalibor TEQUE Fernando MACKEWICZ Carl PETERLIN Matija LEVY Jay A.

  Article in Periodical

  Journal of General Virology, year: 2016, volume: 97, edition: January, DOI

2015

• Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

  EKUMI Kingsley M. PACULOVÁ Hana LENASI Tina POSPÍCHALOVÁ Vendula BOESKEN Christian A. RYBAŘÍKOVÁ Jana BRYJA Vítězslav GEYER Matthias BLAŽEK Dalibor BARBORIC Matjaz

  Article in Periodical

  Nucleic Acids Research, year: 2015, volume: 43, edition: 5, DOI

2014

• The structure and substrate specificity of human Cdk12/Cyclin K

  BÖSKEN Christian A. FARNUNG Lucas HINTERMAIR Corinna SCHACHTER Miriam Merzel VOGEL- BACHMAYR Karin BLAŽEK Dalibor ANAND Kanchan FISHER Robert P. EICK Dirk GEYER Matthias

  Article in Periodical

  NATURE COMMUNICATIONS, year: 2014, volume: 5, edition: 3505, DOI

• Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway

  ŠMERDOVÁ Lenka SVOBODOVÁ Jana KABÁTKOVÁ Markéta KOHOUTEK Jiří BLAŽEK Dalibor MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Carcinogenesis, year: 2014, volume: 35, edition: 11, DOI

2012

• Cyclin K goes with Cdk12 and Cdk13

  KOHOUTEK Jiří BLAŽEK Dalibor

  Article in Periodical

  Cell Division, year: 2012, volume: 7, edition: 12, DOI

• The cyclin K/Cdk12 complex An emerging new player in the maintenance of genome stability

  BLAŽEK Dalibor

  Article in Periodical

  Cell Cycle, year: 2012, volume: 11, edition: 6, DOI

2011

• The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

  BLAŽEK Dalibor KOHOUTEK Jiří BARTHOLOMEEUSEN Koen JOHANSEN Eric HULINKOVÁ Petra LUO Zeping P. CIMERMANCIC Peter ULE Jernej PETERLIN Matija B.

  Article in Periodical

  Genes & Development, year: 2011, volume: 25, edition: 20, DOI

2009

• Cyclin T2 Is Essential for Mouse Embryogenesis

  KOHOUTEK Jiří LI Qintong BLAŽEK Dalibor LUO Zeping JIANG Huimin PETERLIN B Matija

  Article in Periodical

  Molecular and Cellular Biology, year: 2009, volume: 29, edition: 12, DOI