Mgr. Iva Pernicová, Ph.D.

Research specialist, Lukáš Čajánek Research Group: Laboratory of Cilia and Centrosome Biology

correspondence Address:
Kamenice 753/5, 625 00 Brno

office: bldg. F01B1/228
Kamenice 126/3
625 00 Brno

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phone:	+420 549 49 6088
e‑mail:

Basic information

Type

Total number of publications: 17

2017

One reporter for in-cell activity profiling of majority of protein kinase oncogenes

GUDERNOVÁ Iva TRANTÍRKOVÁ Silvie EL GHANNAMOVÁ Barbora FAFÍLEK Bohumil VAŘECHA Miroslav BÁLEK Lukáš HRUBÁ Eva JONÁTOVÁ Lucie JELÍNKOVÁ Iva BOSÁKOVÁ Michaela TRANTÍREK Lukáš MAYER Jiří KREJČÍ Pavel

Article in Periodical

eLife, year: 2017, volume: 6, edition: "e21536", DOI

2016

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

TAYLOR S. Paige BOSÁKOVÁ Michaela VAŘECHA Miroslav BÁLEK Lukáš BÁRTA Tomáš TRANTÍREK Lukáš JELÍNKOVÁ Iva DURAN Ivan VESELÁ Iva FORLENZA Kimberly N. MARTIN Jorge H. HAMPL Aleš BAMSHAD Michael NICKERSON Deborah JAWORSKI Margie L. SONG Jieun WAN KO Hyuk COHN Daniel H. KRAKOW Deborah KREJČÍ Pavel

Article in Periodical

Human Molecular Genetics, year: 2016, volume: 25, edition: 18, DOI
Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short stature syndromes

GUDERNOVÁ Iva VESELA Iva BÁLEK Lukáš BUCHTOVÁ marcela DOSEDELOVA Hana KUNOVÁ Michaela PIVNIČKA Jakub JELÍNKOVÁ Iva ROUBALOVA Lucie KOZUBÍK Alois KREJČÍ Pavel

Article in Periodical

Human Molecular Genetics, year: 2016, volume: 25, edition: 1, DOI

2015

Fibroblast growth factor and canonical WNT/beta-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

BUCHTOVÁ marcela ORALOVÁ Veronika AKLIAN Anie MAŠEK Jan VESELA Iva OUYANG Zhufeng OBADALOVÁ Tereza KONEČNÁ Žaneta SPOUSTOVÁ Tereza POSPÍŠILOVÁ Tereza MATULA Petr VAŘECHA Miroslav BÁLEK Lukáš GUDERNOVÁ Iva JELÍNKOVÁ Iva DURAN Ivan ČERVENKOVÁ Iveta MURAKAMI Shunichi KOZUBÍK Alois DVOŘÁK Petr BRYJA Vítězslav KREJČÍ Pavel

Article in Periodical

Biochimica et Biophysica Acta - Molecular Basis of Disease, year: 2015, volume: 1852, edition: 5, DOI

2014

DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.

SKENDER Belma HOFMANOVÁ Jiřina SLAVÍK Josef JELÍNKOVÁ Iva MACHALA Miroslav MOYER Marry Pat KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

Article in Periodical

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, year: 2014, volume: 1841, edition: 9, DOI
Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway

JELÍNKOVÁ Iva ŠAFAŘÍKOVÁ Barbora BLANAROVA Olga Vondalova SKENDER Belma HOFMANOVÁ Jiřina SOVA Petr MOYER Mary Pat KOZUBÍK Alois KOLAR Zdenek EHRMANN Jiri VACULOVA Alena Hyrslova

Article in Periodical

Biochemical Pharmacology, year: 2014, volume: 92, edition: 3, DOI

2013

Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells

VONDÁLOVÁ BLANÁŘOVÁ Olga JELÍNKOVÁ Iva HYRŠLOVÁ VACULOVÁ Alena SOVA P. HOFMANOVÁ Jiřina KOZUBÍK Alois

Article in Periodical

Cell Proliferation, year: 2013, volume: 46, edition: 6, DOI
Rosiglitazone acts as an efficient modulator of LA-12-induced cytotoxic and cytostatic response of colon cancer cells.

LAUKOVÁ Jarmila JELÍNKOVÁ Iva HOFMANOVÁ Jiřina STRAKOVÁ Nicol SOVA Petr EHRMANN Jiří KOLÁŘ Zdeněk KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

Conference abstract

Year: 2013, type: Conference abstract
Rosiglitazone efficiently sensitizes human colon cancer cells to LA-12-induced apoptosis

LAUKOVÁ Jarmila JELÍNKOVÁ Iva HOFMANOVÁ Jiřina SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

Conference abstract

Year: 2013, type: Conference abstract
The novel combination of rosiglitazone and platinum (IV) compound LA-12 exerts cooperative cytotoxic effects in colon cancer cells associated with activation of mitochondrial apoptotic pathway.

LAUKOVÁ Jarmila JELÍNKOVÁ Iva HOFMANOVÁ Jiřina SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

Conference abstract

Year: 2013, type: Conference abstract