prof. Mgr. Vítězslav Bryja, Ph.D.

2025

• Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε

  HAAG Adrian NEMEC Vaclav JANOVSKÁ Pavlína BARTOŠÍKOVÁ Jana ADHIKARI Bikash MUELLER Juliane SCHWALM Martin P ČADA Štěpán OHMAYER Uli DAUB Henrik KIM Yeojin BORN Florian WOLF Elmar BRYJA Vítězslav KNAPP Stefan

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2025, volume: 68, edition: 1, DOI

• Mechanism of regulation of lymphoid cell migration persistence by casein kinase 1

  ČADA Štěpán GÖMÖRYOVÁ Kristína MARTINKOVÁ Petra BARTOŠÍKOVÁ Jana NĚMEC Václav HAAG Adrian POTĚŠIL David MODRIANSKY Branislav ZDRÁHAL Zbyněk KNAPP Stefan BRYJA Vítězslav

  Conference abstract

  Year: 2025, type: Conference abstract

• Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells

  DRÁPELA Stanislav KVOKAČKOVÁ Barbora SLABÁKOVÁ Eva VYHLÍDALOVÁ KOTRBOVÁ Anna GÖMÖRYOVÁ Kristína FEDR Radek KURFUERSTOVA Daniela ELIAS Martin STUDENT Vladimir LENCESOVA Frederika GANJI Sri Ranjani HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula BRYJA Vítězslav VAN WEERDEN Wytske M PUHR Martin CULIG Zoran BOUCHAL Jan SOUCEK Karel

  Article in Periodical

  CELLULAR ONCOLOGY, year: 2025, volume: 48, edition: 1, DOI

2024

• Analysis of Wnt-related gene expression in primary lymphocytes based on publicly available datasets

  KOLČÁKOVÁ Nela MIKULOVÁ Antónia ČADA Štěpán BRYJA Vítězslav

  Conference abstract

  Year: 2024, type: Conference abstract

• Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein

  KRAVEC Marek ŠEDO Ondrej NEDVEDOVA Jana MICKA Miroslav ŠULCOVÁ Marie ZEZULA Nikodém GÖMÖRYOVÁ Kristína POTĚŠIL David GANJI Sri Ranjani BOLOGNA Sara ČERVENKA Igor ZDRÁHAL Zbyněk HARNOŠ Jakub TRIPSIANES Konstantinos JANKE Carsten BARINKA Cyril BRYJA Vítězslav

  Article in Periodical

  EMBO Journal, year: 2024, volume: 43, edition: 22, DOI

• Casein Kinase 1α fine-tunes NOTCH1 intracellular domain stability and function

  TURETTI Fabio AGOSTINI MAIA Lorena HAJŠMANOVÁ Hana GYBEĽ Tomáš DOKOUPIL Marek BRYJA Vítězslav HARNOŠ Jakub MAŠEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract

• Casein Kinase 1α fine-tunes NOTCH1 intracellular domain stability and functions

  TURETTI Fabio AGOSTINI MAIA Lorena HAJŠMANOVÁ Hana GYBEĽ Tomáš DOKOUPIL Marek BRYJA Vítězslav HARNOŠ Jakub MAŠEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract

• Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling

  NTOURMAS Senem SACHS Martin PACLÍKOVÁ Petra BRÜCKNER Martina BRYJA Vítězslav BEHRENS Jürgen BERNKOPF Dominic B.

  Article in Periodical

  eLife, year: 2024, volume: 13, edition: December, DOI

• ChOP-CT: quantitative morphometrical analysis of the Hindbrain Choroid Plexus by X-ray micro-computed tomography

  PAROBKOVÁ Viktória KOMPANÍKOVÁ Petra LÁZŇOVSKÝ Jakub KAVKOVÁ Michaela HAMPL Marek BUCHTOVÁ Marcela ZIKMUND Tomáš KAISER Jozef BRYJA Vítězslav

  Article in Periodical

  Fluids and Barriers of the CNS, year: 2024, volume: 21, edition: 1, DOI

• Lipidomic analysis of tetraspanin-deficient extracellular vesicles

  SMOLKO Martin KOVÁČ Ondrej VYHLÍDALOVÁ KOTRBOVÁ Anna BÖHMEOVÁ Nina CELÁ Anežka KOTOUČEK Jan SOUČEK Karel BRYJA Vítězslav HLAVÁČKOVÁ POSPÍCHALOVÁ Vendula

  Conference abstract

  Year: 2024, type: Conference abstract