doc. Mgr. Martin Trbušek, Dr.

2016

• Mutations in SF3B1 gene are selected independently on ATM/TP53 status and reduce the time to first treatment in CLL patients.

  HLOŽKOVÁ Michaela FIGULOVÁ Jana NAVRKALOVÁ Veronika MALČÍKOVÁ Jitka ŠMARDOVÁ Jana TOM Nikola BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka TRBUŠEK Martin

  Conference abstract

  Year: 2016, type: Conference abstract

• Pro-apoptotic effects of prima-1met correlate with Noxa gene induction in chronic lymphocytic leukemia cells

  JAŠKOVÁ Zuzana MALČÍKOVÁ Jitka ŠMARDOVÁ Jana BRYCHTOVÁ Yvona DOUBEK Michael TRBUŠEK Martin

  Conference abstract

  Year: 2016, type: Conference abstract

• Studium selekce nepříznivých genomických abnormalit v relapsu chronické lymfocytární leukemie

  PLEVOVÁ Karla MALČÍKOVÁ Jitka BRÁZDILOVÁ Kamila TRBUŠEK Martin DIVÍŠKOVÁ Eva PAVLOVÁ Šárka ŠMARDOVÁ Jana BRYCHTOVÁ Yvona DOUBEK Michael POSPÍŠILOVÁ Šárka

  Conference abstract

  Year: 2016, type: Conference abstract

2015

• Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification

  TE RAA G.D. MOERLAND P.D. LEEKSMA A.C. DERKS I.A. YIGITTOP H. LADDACH N. LODEN-VAN STRAATEN M. NAVRKALOVÁ Veronika TRBUŠEK Martin LUIJKS D.M. ZENZ T. SKOWRONSKA A. HOOGENDOORN M. STANKOVIC T. VAN OERS M.H. ELDERING E. KATER A.P.

  Article in Periodical

  CELL DEATH & DISEASE, year: 2015, volume: 6, edition: august, DOI

• ATM mutations are stable during the course of chronic lymphocytic leukemia.

  FIGULOVÁ Jana NAVRKALOVÁ Veronika BRYCHTOVÁ Yvona MAYER Jiří TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• ATM mutations in major stereotyped CLL subsets: enrichment in subset #2 is associated with unfavourable outcome

  NAVRKALOVÁ Veronika YOUNG E. BALIAKAS P. RADOVÁ Lenka PLEVOVÁ Karla SUTTON LA. MANSOURI L. LJUNGSTROM V. NTOUFA S. DAVIS Z. JULIUSSON G. SMEDBY K. BELESSI Ch. PANAGIOTIDIS P. DAVI F. LANGERAK A. GHIA P. STREFFORD J. OSICER D. STAMATOPOULOS K. POSPÍŠILOVÁ Šárka ROSENQUIST R. TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia

  MALČÍKOVÁ Jitka STAŇO KOZUBÍK Kateřina TICHÝ Boris KANTOROVÁ Barbara PAVLOVÁ Šárka TOM Nikola RADOVÁ Lenka ŠMARDOVÁ Jana PARDY Filip DOUBEK Michael BRYCHTOVÁ Yvona MRÁZ Marek PLEVOVÁ Karla DIVÍŠKOVÁ Eva OLTOVÁ Alexandra MAYER Jiří POSPÍŠILOVÁ Šárka TRBUŠEK Martin

  Article in Periodical

  Leukemia, year: 2015, volume: 29, edition: 4, DOI

• Elimination of mutated p53 protein and induction of p53 downstream genes in chronic lymphocytic leukemia cells using prima-1met.

  JAŠKOVÁ Zuzana MALČÍKOVÁ Jitka ŠMARDOVÁ Jana BRYCHTOVÁ Yvona MAYER Jiří TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• Chronic lymphocytic leukemia cells are highly susceptible to direct inhibition of checkpoint kinase

  ZEMANOVÁ Jana PARUCH Kamil KREJČÍ Lumír SOUČEK Karel HYLSE Ondřej BOUDNÝ Miroslav BORSKÝ Marek OSIČKOVÁ Jitka KHIRSARIYA PrashantKumar ŠEBEJOVÁ Ludmila NAVRKALOVÁ Veronika MALČÍKOVÁ Jitka DIVÍŠKOVÁ Eva BRYCHTOVÁ Yvona MAYER Jiří TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• MicroRNA involvement in DNA damage response and BCR signaling in malignant B cells

  ČERNÁ Kateřina OPPELT Jan RADOVÁ Lenka MUSILOVÁ Kateřina ŠEDA Václav PAVLASOVÁ Gabriela JEŽ Michal TOM Nikola PARDY Filip MALČÍKOVÁ Jitka PLEVOVÁ Karla TICHÝ Boris BRYCHTOVÁ Yvona DOUBEK Michael TRBUŠEK Martin MAYER Jiří KOČA Jaroslav CALOGERO R. POSPÍŠILOVÁ Šárka MRÁZ Marek

  Conference abstract

  Year: 2015, type: Conference abstract