prof. Mgr. Richard Štefl, Ph.D.

2024

• Assembly of the Xrn2/Rat1–Rai1–Rtt103 termination complexes in mesophilic and thermophilic organisms

  DIKUNOVÁ Alžbeta NOSKOVÁ Nikola OVERBECK Jan H. POLÁK Martin STELZIG David ZAPLETAL David KUBÍČEK Karel NOVÁČEK Jiří SPRANGERS Remco ŠTEFL Richard

  Article in Periodical

  Structure, year: 2024, volume: 33, DOI

• Sequence and structural determinants of RNAPII CTD phase-separation and phosphorylation by CDK7

  LINHARTOVÁ Kateřina FALGINELLA Francesco Luca MÁTL Martin ŠEBESTA Marek VÁCHA Robert ŠTEFL Richard

  Article in Periodical

  Nature Communications, year: 2024, volume: 15, edition: 1, DOI

• Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II

  KEOWN Jeremy BAAZAOUI Alaa ŠEBESTA Marek ŠTEFL Richard CARRIQUE Loic FODOR Ervin GRIMES Jonathan M

  Article in Periodical

  Journal of Virology, year: 2024, volume: 98, edition: 5, DOI

2023

• Dicer structure and function: conserved and evolving features

  ZAPLETAL David KUBÍČEK Karel SVOBODA Petr ŠTEFL Richard

  Article in Periodical

  EMBO reports, year: 2023, volume: 24, edition: 7, DOI

• Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

  HAŠANOVÁ Zdenka KLÁPŠŤOVÁ Veronika PORRUA Odil ŠTEFL Richard ŠEBESTA Marek

  Article in Periodical

  Nucleic Acids Research, year: 2023, volume: 51, edition: 6, DOI

• The phosphorylated trimeric SOSS1 complex and RNA polymerase II trigger liquid-liquid phase separation at double-strand breaks

  LONG Qilin ŠEBESTA Marek ŠEDOVÁ Kateřina HALUZA Vojtěch ALAGIA Adele LIU Zhichao ŠTEFL Richard GULLEROVA Monika

  Article in Periodical

  Cell Reports, year: 2023, volume: 42, edition: 12, DOI

2022

• Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly

  KASILIAUSKAITE Aiste KUBÍČEK Karel KLUMPLER Tomáš ZÁNOVÁ Martina ZAPLETAL David KOUTNA Eliska NOVÁČEK Jiří ŠTEFL Richard

  Article in Periodical

  Nucleic acids research, year: 2022, volume: 50, edition: 10, DOI

• Cryo-EM reveals the structural basis for the regulatory function of HEL1 domain in vertebrate DICERs

  ZAPLETAL David KUBÍČEK Karel ZÁNOVÁ Martina MALIK Radek ŠEBESTA Marek NOVÁČEK Jiří SVOBODA Petr ŠTEFL Richard

  Appeared in Conference without Proceedings

  Year: 2022, type: Appeared in Conference without Proceedings

• Structural and functional basis of mammalian microRNA biogenesis by Dicer

  ZAPLETAL David TABORSKA Eliska PASULKA Josef MALIK Radek KUBÍČEK Karel ZÁNOVÁ Martina MUCH Christian ŠEBESTA Marek BUCCHERI Valeria HORVAT Filip JENICKOVA Irena PROCHAZKOVA Michaela PROCHAZKA Jan PINKAS Matyáš NOVÁČEK Jiří JOSEPH Diego F SEDLACEK Radislav BERNECKY Carrie CARROLL Donal ŠTEFL Richard SVOBODA Petr

  Article in Periodical

  Molecular Cell, year: 2022, volume: 82, edition: 21, DOI

2021

• PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC

  APPEL Lisa-Marie FRANKE Vedran BRUNO Melania GRISHKOVSKAYA Irina KASILIAUSKAITE Aiste KAUFMANN Tanja SCHOEBERL Ursula E. PUCHINGER Martin G. KOSTRHON Sebastian EBENWALDNER Carmen ŠEBESTA Marek BELTZUNG Etienne MECHTLER Karl LIN Gen VLASOVA Anna LEEB Martin PAVRI Rushad STARK Alexander AKALIN Altuna ŠTEFL Richard BERNECKY Carrie DJINOVIC-CARUGO Kristina SLADE Dea

  Article in Periodical

  Nature Communications, year: 2021, volume: 12, edition: 1, DOI