prof. Mary Anne O'Connell, PhD.

2024

• Amyloid precursor protein induces reactive astrogliosis

  JAUREGUI Gretsen Velezmoro VUKIĆ Dragana ONYANGO Isaac G ARIAS Carlos NOVOTNY Jan S TEXLOVA Katerina WANG Shanshan KOVACOVICOVA Kristina Locker POLAKOVA Natalie ZELINKOVA Jana CARNA Maria LACOVICH STRAŠIL Valentina HEAD Brian P HAVAS Daniel MISTRIK Martin ZOREC Robert VERKHRATSKY Alexei KEEGAN Liam O'CONNELL Mary Anne RISSMAN Robert STOKIN Gorazd B

  Article in Periodical

  Acta Physiologica, year: 2024, volume: 240, edition: 6, DOI

• An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation

  SINIGAGLIA Ketty CHERIAN Anna DU Qiupei LACOVICH STRAŠIL Valentina VUKIĆ Dragana MELICHEROVÁ Janka MUSILOVÁ Pavla ZERAD Lisa STEJSKAL Stanislav MALIK Radek PROCHAZKA Jan BONDURAND Nadege SEDLACEK Radislav O'CONNELL Mary Anne KEEGAN Liam

  Article in Periodical

  Cell Reports, year: 2024, volume: 43, edition: 8, DOI

2023

• Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous

  KEEGAN Liam HAJJI Khadija O'CONNELL Mary Anne

  Article in Periodical

  Accounts of chemical research, year: 2023, volume: 56, edition: 22, DOI

• RNA PhD Conference 2023

  O'CONNELL Mary Anne MUSILOVÁ Michaela TRUKSOVÁ Barbora

  Conference

  Year: 2023, type: Conference

2022

• ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations

  HAJJI Khadija SEDMÍK Jiří CHERIAN Anna AMORUSO Damiano KEEGAN Liam O'CONNELL Mary Anne

  Article in Periodical

  RNA, year: 2022, volume: 28, edition: 10, DOI

• The mechanical regulation of RNA binding protein hnRNPC in the failing heart

  MARTINO Fabiana VARADARAJAN Nandan Mysore PERESTRELO Ana Rubina HEJRET Václav DURIKOVA Helena VUKIĆ Dragana HORVATH Vladimir CAVALIERI Francesca CARUSO Frank ALBIHLAL Waleed S GERBER Andre P O'CONNELL Mary Anne VAŇÁČOVÁ Štěpánka PAGLIARI Stefania FORTE Giancarlo

  Article in Periodical

  Science Translational Medicine, year: 2022, volume: 14, edition: 672, DOI

2021

• ADAR RNA Modifications, the Epitranscriptome and Innate Immunity

  QUIN Jaclyn Elizabeth SEDMÍK Jiří VUKIĆ Dragana KHAN Anzer KEEGAN Liam O'CONNELL Mary Anne

  Article in Periodical

  Trends in Biochemical Sciences, year: 2021, volume: 46, edition: 9, DOI

• Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy

  MAROOFIAN Reza SEDMÍK Jiří MAZAHERI Neda SCALA Marcello ZAKI Maha S. KEEGAN Liam AZIZIMALAMIRI Reza ISSA Mahmoud SHARIATI Gholamreza SEDAGHAT Alireza BEETZ Christian BAUER Peter GALEHDARI Hamid O'CONNELL Mary Anne HOULDEN Henry

  Article in Periodical

  Journal of Medical Genetics, year: 2021, volume: 58, edition: 7, DOI

• Generation of stable cell lines for the screening of inhibitors of the ADAR enzymes

  O'CONNELL Mary

  Year: 2021, type:

• Interplays of different types of epitranscriptomic mRNA modifications

  RENGARAJ Praveenkumar OBRDLÍK Aleš VUKIĆ Dragana VARADARAJAN Nandan Mysore KEEGAN Liam VAŇÁČOVÁ Štěpánka O'CONNELL Mary Anne

  Article in Periodical

  RNA Biology, year: 2021, volume: 18, edition: S1, DOI