Vlad-Constantin Ursachi

2025

• Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer

  ZLÍNSKÁ Vladimíra FEKETOVÁ Zuzana CZYREK Aleksandra Anna CHUDZIAN Julia ZIVKOVIC Martina Lenarcic URSACHI Vlad-Constantin DUDEJA Pooja FAFÍLEK Bohumil RYNEŠ Jan RICO LLANOS Gustavo KOUDELKA Adolf ROY Tanaya BIADUN Martyna RAŠKOVÁ Vendula SVOZILOVÁ Kateřina STROBLOVÁ Michaela KRZYSCIK Mateusz HRISTOVA Kalina KROWARSCH Daniel TRANTÍRKOVÁ Silvie ZAKRZEWSKA Malgorzata TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI

2024

• Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2

  NĚMEC Václav REMEŠ Marek BEŇOVSKÝ Petr BÖCK Michael Christopher ŠRANKOVÁ Eliška WONG Jong Fu JULIEN Cros WILLIAMS Eleanor TSE Lap Hang SMIL David ENSAN Deeba ISAAC Methvin B AL-AWAR Rima GOMOLKOVÁ Regína URSACHI Vlad-Constantin FAFÍLEK Bohumil KAHOUNOVA Zuzana VICHOVA Rachel VACEK Ondrej BERGER Benedict-Tilman WELLS Carrow I CORONA Cesear R VASTA James D ROBERS Matthew B KREJČÍ Pavel SOUČEK Karel BULLOCK Alex N KNAPP Stefan PARUCH Kamil

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2024, volume: 67, edition: 15, DOI

• Ligand bias underlies differential signaling of multiple FGFs via FGFR1

  KARL Kelly NUALA Del Piccolo LIGHT Taylor ROY Tanaya DUDEJA Pooja URSACHI Vlad-Constantin FAFÍLEK Bohumil KREJČÍ Pavel HRISTOVA Kalina

  Article in Periodical

  elife, year: 2024, volume: 12, edition: April 2024, DOI