Mgr. Zuzana Jašková, Ph.D.

Researcher, Biobank and CELSPAC Laboratories

correspondence Address:
Kotlářská 267/2, 611 37 Brno

office: bldg. D29/1S118
Kamenice 753/5
625 00 Brno

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phone:	+420 549 49 4793
e‑mail:

Inactive employment status

Basic information

Type

Total number of publications: 18

2020

PRIMA-1MET cytotoxic effect correlates with p53 protein reduction in TP53-mutated chronic lymphocytic leukemia cells

JAŠKOVÁ Zuzana PAVLOVÁ Šárka MALČÍKOVÁ Jitka BRYCHTOVÁ Yvona TRBUŠEK Martin

Article in Periodical

Leukemia Research, year: 2020, volume: 89, edition: FEB 2020, DOI

2019

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells

BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana OLTOVÁ Alexandra ŠEDA Václav MRÁZ Marek JAROŠ Josef JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela BRYCHTOVÁ Yvona SOUČEK Karel DRÁPELA Stanislav KAŠPÁRKOVÁ Marie MAYER Jiří PARUCH Kamil TRBUŠEK Martin

Article in Periodical

Haematologica, year: 2019, volume: 104, edition: 12, DOI
Potenciál inhibice proteinu checkpoint kinase 1 u chronické lymfocytární leukémie s mutacemi v genu TP53.

BOUDNY´ Miroslav ZEMANOVA´ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana ŠEDA Václav MRÁZ Marek OLTOVÁ Alexandra JAROŠ J. JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

Conference abstract

Year: 2019, type: Conference abstract

2018

Inovativní inhibitor proteinu CHK1 indukuje apoptózu u buněk chronické lymfocytární leukémie s mutacemi v genu TP53

BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan AMRUZ ČERNÁ Kateřina MRÁZ Marek OLTOVÁ Alexandra JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela ŠEDA Václav BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

Conference abstract

Year: 2018, type: Conference abstract
Selective CHK1 inhibitor MU380 exhibits single-agent activity against chronic lymphocytic leukemia cells with TP53 mutations

BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana MRÁZ Marek OLTOVÁ Alexandra JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela ŠEDA Václav BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

Conference abstract

Year: 2018, type: Conference abstract

2017

Sada pro detekci přítomnosti mutací v genu ATM u pacientů s CLL

TRBUŠEK Martin JAŠKOVÁ Zuzana KUBEŠOVÁ Blanka NAVRKALOVÁ Veronika ŠEBEJOVÁ Ludmila PLEVOVÁ Karla

Year: 2017

2016

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells

ZEMANOVÁ Jana HYLSE Ondřej COLLAKOVA Jana VESELY Pavel OLTOVÁ Alexandra BORSKÝ Marek ZÁPRAŽNÁ Kristína KAŠPÁRKOVÁ Marie JANOVSKÁ Pavlína VERNER Jan KOHOUTEK Jiri DZIMKOVA Marta BRYJA Vítězslav JAŠKOVÁ Zuzana BRYCHTOVÁ Yvona PARUCH Kamil TRBUŠEK Martin

Article in Periodical

Oncotarget, year: 2016, volume: 7, edition: 38, DOI
Pro-apoptotic effects of prima-1met correlate with Noxa gene induction in chronic lymphocytic leukemia cells

JAŠKOVÁ Zuzana MALČÍKOVÁ Jitka ŠMARDOVÁ Jana BRYCHTOVÁ Yvona DOUBEK Michael TRBUŠEK Martin

Conference abstract

Year: 2016, type: Conference abstract

2015

Elimination of mutated p53 protein and induction of p53 downstream genes in chronic lymphocytic leukemia cells using prima-1met.

JAŠKOVÁ Zuzana MALČÍKOVÁ Jitka ŠMARDOVÁ Jana BRYCHTOVÁ Yvona MAYER Jiří TRBUŠEK Martin

Conference abstract

Year: 2015, type: Conference abstract
NOD/SCID IL2R gamma-null mouse xenograft model of human p53-mutated chronic lymphocytic leukemia and ATM-mutated mantle cell lymphoma using permanent cell lines

VERNER Jan TRBUŠEK Martin CHOVANCOVÁ Jana JAŠKOVÁ Zuzana MOULIS Mojmír FOLBER František HALOUZKA Roman MAYER Jiří POSPÍŠILOVÁ Šárka DOUBEK Michael

Article in Periodical

Leukemia & Lymphoma, year: 2015, volume: 56, edition: 11, DOI