prof. RNDr. Jiřina Hofmanová, CSc.

2021

• Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells

  HOFMANOVÁ Jiřina SLAVIK Josef CIGANEK Miroslav OVESNÁ Petra TYLICHOVA Zuzana KARASOVÁ Martina ZAPLETAL Ondrej STRAKOVA Nicol PROCHÁZKOVÁ Jiřina BOUCHAL Jan KOLAR Zdenek EHRMANN Jiri LEVKOVA Monika HUSKOVA Zlatka SKALICKY Pavel KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 13, DOI

2019

• Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models

  ZAPLETAL Ondřej PROCHÁZKOVÁ Jiřina DUBEC Vít HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2019, volume: 412, edition: JAN, DOI

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells.

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan

  Article in Periodical

  JOURNAL OF CELLULAR BIOCHEMISTRY, year: 2018, volume: 119, edition: 6, DOI

2017

• Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation

  TYLICHOVÁ Zuzana STRAKOVÁ Nicol VONDRÁČEK Jan VACULOVA A.H. KOZUBÍK Alois HOFMANOVÁ Jiřina

  Article in Periodical

  JOURNAL OF NUTRITIONAL BIOCHEMISTRY, year: 2017, volume: 39, edition: January, DOI

• Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models

  ZAPLETAL Ondřej TYLICHOVÁ Zuzana NEČA Jiří KOHOUTEK Jiří MACHALA Miroslav MILCOVA A. POKORNA Michaela TOPINKA Jan MOYER M.P. HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  ARCHIVES OF TOXICOLOGY, year: 2017, volume: 91, edition: 5, DOI

• Butyrate plays a supporting role in alterations of lipidome induced by DHA in colon cancer cells

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois VONDRÁČEK Jan HOFMANOVÁ Jiřina

  Conference abstract

  Year: 2017, type: Conference abstract

• Dietary fatty acids specifically modulate phospholipid patternin colon cells with distinct differentiation capacities

  HOFMANOVÁ Jiřina SLAVÍK Josef OVESNÁ Petra TYLICHOVÁ Zuzana VONDRÁČEK Jan STRAKOVÁ Nicol HYRŠLOVÁ VACULOVÁ Alena CIGANEK Miroslav KOZUBÍK Alois KNOPFOVÁ Lucia ŠMARDA Jan MACHALA Miroslav

  Article in Periodical

  European Journal of Nutrition, year: 2017, volume: 56, edition: 4, DOI

• n-3 Polyunsaturated fatty acids alleviate benzo[a]pyrene toxicity in human colon cancer cell lines

  TYLICHOVÁ Zuzana NEČA Jiří MACHALA Miroslav TOPINKA Jan MILCOVÁ Alena HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Conference abstract

  Year: 2017, type: Conference abstract

2016

• Cisplatin or LA-12-mediated stimulation of TRAIL-induced apoptosis in human prostate cancer cells involves Bax/Bak-dependent mitochondria activation

  VONDÁLOVÁ BLANÁŘOVÁ Olga HERŮDKOVÁ Jarmila ŠAFAŘÍKOVÁ Barbora KRKOŠKA Martin TOMÁNKOVÁ Silvie PERNICOVÁ Zuzana SOUČEK Karel BOUCHAL Jan KHARAISHVILI G KRÁL M SOVA P HOFMANOVÁ Jiřina KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2016, type: Conference abstract