Mgr. Ondřej Zapletal, Ph.D.

2024

• Functional analysis of PLAUR alternative splicing isoforms and they role in the development of immunopathological reactions

  KULÍŠKOVÁ Petra ZAPLETAL Ondřej SLANINA Peter ŠTÍCHOVÁ Julie VLKOVÁ Marcela LITZMAN Jiří NĚMEC Petr BAROŠ Jan BALLONOVÁ Lucie SOUČEK Přemysl FREIBERGER Tomáš

  Conference abstract

  Year: 2024, type: Conference abstract

2023

• Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity

  BALLONOVÁ Lucie SOUČEK Přemysl SLANINA Peter RÉBLOVÁ Kamila ZAPLETAL Ondřej VLKOVÁ Marcela HAKL Roman BÍLY Viktor GROMBIŘÍKOVÁ Hana SVOBODOVÁ Eliška KULÍŠKOVÁ Petra ŠTÍCHOVÁ Julie SOBOTKOVÁ Marta RADANA Zachová HANZLÍKOVÁ Jana VACHOVÁ Martina KRÁLÍČKOVÁ Pavlína KRČMOVÁ Irena JESEŇÁK Miloš FREIBERGER Tomáš

  Article in Periodical

  FRONTIERS IN GENETICS, year: 2023, volume: 14, edition: July 2023, DOI

2022

• Different patterns of immune system activation in hereditary angioedema based on disease severity

  BALLONOVÁ Lucie SOUČEK Přemysl HAKL Roman SLANINA Peter VLKOVÁ Marcela SOBOTKOVÁ Marta KRÁLÍČKOVÁ Pavlína KRČMOVÁ I. HANZLÍKOVÁ Jana VACHOVÁ M. JESENÁK Miloš GROMBIŘÍKOVÁ Hana RÉBLOVÁ Kamila BÍLY Viktor ZAPLETAL Ondřej FREIBERGER Tomáš

  Conference abstract

  Year: 2022, type: Conference abstract

2021

• Deregulation of signaling pathways controlling cell survival and proliferation in cancer cells alters induction of cytochrome P450 family 1 enzymes

  KRKOŠKA Martin SVOBODOVÁ Jana KABÁTKOVÁ Markéta ZAPLETAL Ondřej HYRŠLOVÁ VACULOVÁ Alena NEKVINDOVÁ Jana VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2021, volume: 461, edition: September, DOI

2019

• Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models

  ZAPLETAL Ondřej PROCHÁZKOVÁ Jiřina DUBEC Vít HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2019, volume: 412, edition: JAN, DOI

• In vitro and in vivo genotoxicity of oxygenated polycyclic aromatic hydrocarbons

  MCCARRICK Sarah CUNHA Virginia ZAPLETAL Ondřej VONDRÁČEK Jan DREIJ Kristian

  Article in Periodical

  Environmental Pollution, year: 2019, volume: 246, edition: MAR 2019, DOI

2018

• Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation

  HYZDALOVA M. PIVNIČKA Jakub ZAPLETAL Ondřej VAZQUEZ-GOMEZ G. MATTHEWS J. NEČA Jiří PĚNČÍKOVÁ Kateřina MACHALA M. VONDRÁČEK Jan

  Article in Periodical

  Toxicological sciences, year: 2018, volume: 165, edition: 2, DOI

• INHIBITION OF P300/CBP REDUCES CYP1A1 INDUCTION IN CANCER CELL MODELS DERIVED FROM THE LIVER OR COLON EPITHELIUM

  KRKOŠKA Martin SVOBODOVÁ Jana ZAPLETAL Ondřej KARASOVÁ Martina HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2018, type: Conference abstract

2017

• Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models

  ZAPLETAL Ondřej TYLICHOVÁ Zuzana NEČA Jiří KOHOUTEK Jiří MACHALA Miroslav MILCOVA A. POKORNA Michaela TOPINKA Jan MOYER M.P. HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  ARCHIVES OF TOXICOLOGY, year: 2017, volume: 91, edition: 5, DOI

2016

• Deregulation of the AhR-dependent CYP1 expression under conditions modulating contact inhibition or cell proliferation in liver cell models

  SVOBODOVÁ Jana ROGOWSKI Petr KABÁTKOVÁ Markéta ZAPLETAL Ondřej MACHALA Miroslav VONDRÁČEK Jan

  Conference abstract

  Year: 2016, type: Conference abstract