Mgr. Jan Raška, Ph.D.

Research specialist, Dáša Bohačiaková Research Group: Neurobiology of the Development and Disease

correspondence Address:
Kamenice 753/5, 625 00 Brno

office: bldg. F01B1/1S13a
Kamenice 126/3
625 00 Brno

phone:	+420 549 49 6989
e‑mail:

social and academic networks:

Basic information

Supervision

Qualifications

Publications

Type

Total number of publications: 29

2024

2. Offsite Meeting of the Department of Histology and Embryology (ÚHE): Advancing Science and Collaboration

HUTEČKOVÁ Barbora KŘIVÁNEK Jan SUMBALOVÁ HOLUBCOVÁ Zuzana BREZAK Matea AĆIMOVIĆ Ivana PORTAKAL Türkan DUMKOVÁ Jana MORÁŇ Lukáš HAMPL Aleš MAKIEIEVA Yelyzaveta VÁŇOVÁ Tereza BOHAČIAKOVÁ Dáša CHOCHOLA Václav JAROŠ Josef ČIMBOROVÁ Katarína KOUTNÁ Irena BOSÁKOVÁ Michaela BÁRTA Tomáš HAVLÍČEK Vítězslav KLOUDOVÁ Soňa JONGEN HERŮDKOVÁ Jarmila GONZÁLEZ LÓPEZ Marcos BENÁK Leoš AZAM Maryam TUAIMA GORBULINA Margarita LAVICKÝ Josef ŠTRUNCOVÁ Marina MIKULENKOVÁ Erika CAKMAKCI Riza Can VAŇHARA Petr PELKOVÁ Vendula POZO KOTASOVÁ Hana KAVKOVÁ Michaela TAUŠ Petr VYSLOUŽIL David ÇELIKER Canan AMRUZ ČERNÁ Kateřina VAŠKOVICOVÁ Naděžda SOURALOVÁ Tereza POROKH Volodymyr KYJOVSKÁ Drahomíra KROČIANOVÁ Daniela CAPANDOVÁ Michaela SEDLÁKOVÁ Veronika FEDOROVÁ Veronika RAŠKA Jan SATKOVÁ Miriam FOJTÍK Petr PLEŠINGROVÁ Klára CESNÁRIKOVÁ Soňa SEDMÍK Jiří HŘÍBKOVÁ Hana MEĆAVA Marko HARMANEC Adam POSPÍŠILOVÁ Veronika BOČKOVÁ Tami BOSÁKOVÁ Veronika BOGDANOVIČ Adam ZDRÁHAL Zbyněk RAKULTSEV Vladislav BUCHTOVÁ Marcela BÁRTOVÁ Simona GINTAR Petr KOLEDOVÁ Zuzana Vincent Alexander Haneen Riadh Ali DEVOTO Victorio Martin

Year: 2024, type:
Generation of the Human iPSC Line from Spontaneous Late-Onset Alzheimer's Disease Patient with ApoE3/3 Genotype and Sex-, Age-, and ApoE-Matched Healthy Control

KADÁKOVÁ Soňa RAŠKA Jan HŘÍBKOVÁ Hana FEDOROVÁ Veronika SEDMÍK Jiří PLEŠINGROVÁ Klára SHEARDOVÁ Kateřina BOHAČIAKOVÁ Dáša

Article in Periodical

Stem cell research, year: 2024, volume: 74, edition: February 2024, DOI
The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease

JENSEN Anne Mette G RAŠKA Jan FOJTÍK Petr MONTI Giulia LUNDING Melanie BÁRTOVÁ Simona POSPÍŠILOVÁ Veronika VAN DER LEE Sven J DONGEN Jasper Van BOSSAERTS Liene BROECKHOVEN Christine Van DOLS-ICARDO Oriol LLÉO Alberto BELLINI Sonia GHIDONI Roberta HULSMAN Marc PETSKO Gregory A SLEEGERS Kristel BOHAČIAKOVÁ Dáša HOLSTEGE Henne ANDERSEN Olav M

Article in Periodical

Proceedings of the National Academy of Sciences of the United States of America, year: 2024, volume: 121, edition: 37, DOI

2023

Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development

VÁŇOVÁ Tereza SEDMÍK Jiří RAŠKA Jan AMRUZ ČERNÁ Kateřina TAUŠ Petr POSPÍŠILOVÁ Veronika NEZVEDOVÁ Markéta FEDOROVÁ Veronika KADÁKOVÁ Soňa KLÍMOVÁ Hana CAPANDOVÁ Michaela ORVISKÁ Petra FOJTÍK Petr BÁRTOVÁ Simona PLEVOVÁ Karla SPÁČIL Zdeněk HŘÍBKOVÁ Hana BOHAČIAKOVÁ Dáša

Article in Periodical

CELL REPORTS, year: 2023, volume: 42, edition: 11, DOI
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

NEMERGUT Michal MARQUES Sérgio Manuel UHRÍK Lukáš VÁŇOVÁ Tereza NEZVEDOVÁ Markéta GADARA Darshak Chandulal JHA Durga TULIS Jan NOVÁKOVÁ Veronika PLANAS IGLESIAS Joan KUNKA Antonín LEGRAND Anthony Thomas P HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika SEDMÍK Jiří RAŠKA Jan PROKOP Zbyněk DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk HERNYCHOVÁ Lenka BEDNÁŘ David MAREK Martin

Article in Periodical

Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI
Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

FEDOROVÁ Veronika POSPÍŠILOVÁ Veronika VÁŇOVÁ Tereza AMRUZ ČERNÁ Kateřina ABAFFY Pavel SEDMÍK Jiří RAŠKA Jan VOCHYÁNOVÁ Simona MATŮŠOVÁ Zuzana HOUSEROVÁ Jana VALIHRACH Lukáš HODNÝ Zdeněk BOHAČIAKOVÁ Dáša

Article in Periodical

MOLECULAR ONCOLOGY, year: 2023, volume: 17, edition: 4, DOI
Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits

NEZVEDOVÁ Markéta JHA Durga VÁŇOVÁ Tereza GADARA Darshak Chandulal KLÍMOVÁ Hana RAŠKA Jan OPÁLKA Lukáš BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk

Article in Periodical

Analytical Chemistry, year: 2023, volume: 95, edition: 6, DOI

2022

Cerebral organoids in disease modeling.

SEDMÍK Jiří VÁŇOVÁ Tereza RAŠKA Jan AMRUZ ČERNÁ Kateřina POSPÍŠILOVÁ Veronika FEDOROVÁ Veronika FOJTÍK Petr VOCHYÁNOVÁ Simona KLÍMOVÁ Hana PLEŠINGROVÁ Klára TAUŠ Petr PLEVOVÁ Karla NEZVEDOVÁ Markéta SPÁČIL Zdeněk CAPANDOVÁ Michaela ORVISKÁ Petra BENEŠOVÁ Z. ABAFY P. VALIHRACH L. HOUSEROVÁ Jana

Conference abstract

Year: 2022, type: Conference abstract
Endocrine-disrupting chemicals affect Sertoli TM4 cell functionality through dysregulation of gap junctional intercellular communication in vitro

YAWER Affiefa SYCHROVÁ Eliška RAŠKA Jan BABICA Pavel SOVADINOVÁ Iva

Article in Periodical

Food and Chemical Toxicology, year: 2022, volume: 164, edition: June 2022, DOI
Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids

BARÁK Martin FEDOROVÁ Veronika POSPÍŠILOVÁ Veronika RAŠKA Jan VOCHYÁNOVÁ Simona SEDMÍK Jiří HŘÍBKOVÁ Hana KLÍMOVÁ Hana VÁŇOVÁ Tereza BOHAČIAKOVÁ Dáša

Article in Periodical

Stem Cell Reviews and Reports, year: 2022, volume: 18, edition: 2, DOI

Projects

Teaching

10 reasons why you will fall in love with MU

Ask our ambassador

Read about research at MU

Mgr. Jan Raška, Ph.D.

2024

2. Offsite Meeting of the Department of Histology and Embryology (ÚHE): Advancing Science and Collaboration

Generation of the Human iPSC Line from Spontaneous Late-Onset Alzheimer's Disease Patient with ApoE3/3 Genotype and Sex-, Age-, and ApoE-Matched Healthy Control

The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease

2023

Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development

Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits

2022

Cerebral organoids in disease modeling.

Endocrine-disrupting chemicals affect Sertoli TM4 cell functionality through dysregulation of gap junctional intercellular communication in vitro

Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids