Mgr. Tomáš Loja, Ph.D.

2021

• Disruption of NAP1 genes in Arabidopsis thaliana suppresses the fas1 mutant phenotype, enhances genome stability and changes chromatin compaction

  KOLÁŘOVÁ Karolína NEŠPOR DADEJOVÁ Martina LOJA Tomáš LOCHMANOVÁ Gabriela SÝKOROVÁ Eva DVOŘÁČKOVÁ Martina

  Article in Periodical

  The Plant Journal, year: 2021, volume: 106, edition: 1, DOI

• FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

  ŠEDA Václav VOJÁČKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš MLADONICKÁ PAVLASOVÁ Gabriela ZICHA Daniel KUDLIČKOVÁ PEŠKOVÁ Marie KŘIVÁNEK Jan MATULOVÁ Květoslava KŘEN Leoš BENES V. LITZMANOVÁ Markéta BORSKÝ Marek OPPELT Jan VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna TAN Z. ZHANG S.X. DOUBEK Michael AMRUZ ČERNÁ Kateřina MAYER Jiří MRÁZ Marek

  Article in Periodical

  Blood, year: 2021, volume: 138, edition: 9, DOI

• FoxO1-GAB1 Axis Regulates Homing Capacity and Tonic AKT Activity in Chronic Lymphocytic Leukemia: Novel Therapeutic Target.

  ŠEDA Václav VOJÁČKOVÁ E. ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA Daniel VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna TAN Zhuowen ZHANG Shelley DOUBEK Michael MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• GAB1 – novel regulator of migration capacity and tonic AKT activity in CLL: Implications for combinatorial therapy with BCR inhibitors.

  ŠEDA Václav HOFERKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA Daniel VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna DOUBEK Michael MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• GAB1 Regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia: novel therapeutic target

  MRÁZ Marek ŠEDA Václav HOFERKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA Daniel VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna DOUBEK Michael MAYER Jiří

  Conference abstract

  Year: 2021, type: Conference abstract

• GAB1 reguluje tonickou AKT signalizaci a migraci buněk chronické lymfatické leukémie: implikace pro kombinační léčbu s BCR inhibitory.

  ŠEDA Václav VOJÁČKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA D. VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna TAN Zhuowen ZHANG Shelley DOUBEK Michael MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up

  ROMŽOVÁ Marianna SMITALOVÁ Dagmar HYNŠT Jakub TOM Nikola LOJA Tomáš HERUDKOVÁ Zdeňka JURČEK Tomáš STEJSKAL Lukas ŽÁČKOVÁ Daniela MAYER Jiří RÁČIL Zdeněk ČULEN Martin

  Article in Periodical

  British journal of haematology, year: 2021, volume: 194, edition: 3, DOI

• Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro

  LEDEREROVÁ Aneta DOSTÁLOVÁ Lenka KOZLOVÁ Veronika PESCHELOVÁ Helena LADUNGOVÁ Adriana ČULEN Martin LOJA Tomáš VERNER Jan POSPÍŠILOVÁ Šárka ŠMÍDA Michal MANČÍKOVÁ Veronika

  Article in Periodical

  Journal for ImmunoTherapy of Cancer, year: 2021, volume: 9, edition: 8, DOI

• In vivo antigen-negative escape to CART-19 caused by CD19 promotor hypermethylation.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta KOZLOVÁ Veronika PESCHELOVÁ Helena LADUNGOVÁ Adriana LOJA Tomáš VERNER Jan POSPÍŠILOVÁ Šárka MANČÍKOVÁ Veronika ŠMÍDA Michal

  Conference abstract

  Year: 2021, type: Conference abstract

• Palbociclib and ponatinib induce regression of acute myeloid leukemia in patient-derived xenograft model.

  BUŠA Daniel LOJA Tomáš JEŽÍŠKOVÁ Ivana FOLTA Adam MAYER Jiří ČULEN Martin

  Conference abstract

  Year: 2021, type: Conference abstract