Mgr. Adriana Ladungová

2024

• ANALYSIS OF ALTERNATIVE THERAPEUTIC OPTIONS FOR ACUTE MYELOID LEUKEMIA PATIENTS RESISTANT TO VENETOCLAX BASED ON DRUG SCREENING AND EXPRESSION PROFILING

  STYLIANOU Filio LADUNGOVÁ Adriana HÝL Jan BUŠA Daniel ČULEN Martin WEINBERGEROVÁ Barbora MAYER Jiří ŠMÍDA Michal

  Conference abstract

  Year: 2024, type: Conference abstract

• EXPLORING VENETOCLAX RESISTANCE MECHANISMS IN AML CELLS THROUGH GENOME-WIDE CRISPR SCREENS AND DRUG PROFILING

  LADUNGOVÁ Adriana STYLIANOU Filio PESCHELOVÁ Helena LODHI Yusuf DOSTÁLOVÁ Lenka GOTTUMUKKALA Narendra Varma ŠMÍDA Michal

  Conference abstract

  Year: 2024, type: Conference abstract

• Novel casein kinase 1 alpha inhibitors for the treatment of resistant AML and solid tumors

  JANOVSKÁ Pavlína RADASZKIEWICZ Tomasz Witold PROCHAZKOVA P PRIŠTICOVÁ Ingrid PLEŠINGEROVÁ Hana ČULEN Martin ŠMÍDA Michal BUŠA Daniel LADUNGOVÁ Adriana MAIER Lukáš HAVEL Štěpán MAYER Jiří SCHEER A PARUCH Kamil BRYJA Vítězslav

  Conference abstract

  Year: 2024, type: Conference abstract

2023

• CRISPR/Cas9 technology as a useful tool in the study of chornic lymphocytic leukemia.

  PESCHELOVÁ Helena MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• CRISPR/Cas9 technology as a useful tool in the study of chronic lymphocytic leukemia.

  PESCHELOVÁ Helena KOZLOVÁ Veronika MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Exploring the mechanisms of Venetoclax resistence via drug screening and genome-wide CRISPR screening.

  LADUNGOVÁ Adriana PESCHELOVÁ Helena DOSTÁLOVÁ Lenka LODHI Yusuf GOTTUMUKKALA Narendra Varma MAYER Jiří ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Chasing the epigenetic landscape to enhance CAR-T cell activity py preventing CD19 antigen escape in relapsed models.

  GOTTUMUKKALA Narendra Varma LEDEREROVÁ Aneta DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana LODHI Yusuf ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Identificationof novel therapeutic options for venetoclax-resistant AML cells through drug repurposing.

  LADUNGOVÁ Adriana BUŠA Daniel LODHI Yusuf HÝL Jan ČULEN Martin ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

2022

• . Drug repurposing for venetoclax-resistant acute myeloid leukemia.

  LADUNGOVÁ Adriana BUŠA Daniel LODHI Yusuf HÝL Jan ČULEN Martin ŠMÍDA Michal

  Conference abstract

  Year: 2022, type: Conference abstract

• Combined drug and CRISPR/CAS9 screening reveals specific targets for SF3B1- and NOTCH1- mutated CLL cells.

  DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika GOTTUMUKKALA Narendra Varma LODHI Yusuf ŠMÍDA Michal

  Conference abstract

  Year: 2022, type: Conference abstract