Mgr. Jan Brezovský, Ph.D.

2025

• Discovery of new inhibitors of nuclease MRE11

  NIKULENKOV Fedor CARBAIN Benoit Jean-Pierre BISWAS Raktim HAVEL Štěpán PROCHÁZKOVÁ Jana SISÁKOVÁ Alexandra ZACPALOVÁ Magdaléna CHAVDAROVA Melita MARINI PALOMEQUE María Victoria VŠIANSKÝ Vít WEISOVÁ Veronika SLÁVIKOVÁ Kristína BIRADAR Dhanraj Omprakash KHIRSARIYA PrashantKumar VITEK Marco SEDLAK David BARTUNEK Petr DANIEL Lukáš BREZOVSKÝ Jan DAMBORSKÝ Jiří PARUCH Kamil KREJČÍ Lumír

  Article in Periodical

  European Journal of Medicinal Chemistry, year: 2025, volume: 285, edition: March, DOI

2024

• Exploring the properties of cohesin-dockerin interactions under application-relevant conditions

  JANKOVIČOVÁ Barbora FERREIRA DA SILVA Miguel Joao SURPETA Bartłomiej BREZOVSKÝ Jan DVOŘÁK Pavel

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

• Investigating the properties of cohesin-dockerin interactions in biotechnologically relevant conditions

  JANKOVIČOVÁ Barbora FERREIRA DA SILVA Miguel Joao SURPETA Bartłomiej BREZOVSKÝ Jan DVOŘÁK Pavel

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

2023

• Substituted aminothiazoles as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: United States Patent and Trademark Office, state: United States of America, patent's number: US11584742, year: 2023

• Substituted aminothiazoles as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: Israel Patent Office, state: Israel, patent's number: IL277866, year: 2023

• Thermostable FGF2 polypeptide, use thereof

  DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela

  Patent

  Publisher: Canadian Intellectual Property Office, state: Canada, patent's number: CA3006388, year: 2023

• Thermostable FGF2 polypeptide, use thereof

  DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela

  Patent

  Publisher: United States Patent and Trademark Office, state: United States of America, patent's number: US11746135B2, year: 2023

• Thermostable FGF2 Polypeptide, Use Thereof

  DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela

  Patent

  Publisher: Intellectual Property India, state: India, patent's number: IN485239, year: 2023

2022

• Substituted aminothiazoles as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: IP Australia, state: Australia, patent's number: AU2019256670, year: 2022

• ヌクレアーゼの阻害剤としての置換アミノチアゾール

  PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: Japan Patent Office (JPO), state: Japan, patent's number: JP7175031, year: 2022