Mgr. Michal Šmída, Dr. rer. nat.

2023

• Genome-wide CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation in rituximab-resistant cells.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Genome-wide CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Chasing the epigenetic landscape to enhance CAR-T cell activity py preventing CD19 antigen escape in relapsed models.

  GOTTUMUKKALA Narendra Varma LEDEREROVÁ Aneta DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana LODHI Yusuf ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Identification of novel targets that upregulate CD20 expression in rituximab-resistant cells with the use of genomewide CRISPR screening.

  DOSTÁLOVÁ Lenka LEDEREROVÁ Aneta PESCHELOVÁ Helena LOJA Tomáš ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Identificationof novel therapeutic options for venetoclax-resistant AML cells through drug repurposing.

  LADUNGOVÁ Adriana BUŠA Daniel LODHI Yusuf HÝL Jan ČULEN Martin ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Nově identifikovaná varianta v genu CYCS u rodiny s trombocytopenií typu 4 a její funkční dopad.

  ŠTIKA Jiří VRZALOVÁ Zuzana STAŇO KOZUBÍK Kateřina PEŠOVÁ Michaela PALUŠOVÁ Veronika DOSTÁLOVÁ Lenka BLAHÁKOVÁ Ivona RADOVÁ Lenka ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

  Conference abstract

  Year: 2023, type: Conference abstract

• Varianta v genu CYCS způsobující trombocytopenii 4 zvyšuje kaspázovou aktivitu.

  ŠTIKA Jiří VRZALOVÁ Zuzana STAŇO KOZUBÍK Kateřina PEŠOVÁ Michaela PALUŠOVÁ Veronika DOSTÁLOVÁ Lenka BLAHÁKOVÁ Ivona RADOVÁ Lenka SEDLÁKOVÁ Petra SONNEK Radim ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

  Conference abstract

  Year: 2023, type: Conference abstract

2022

• . Drug repurposing for venetoclax-resistant acute myeloid leukemia.

  LADUNGOVÁ Adriana BUŠA Daniel LODHI Yusuf HÝL Jan ČULEN Martin ŠMÍDA Michal

  Conference abstract

  Year: 2022, type: Conference abstract

• A GP1BA Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome

  SKALNÍKOVÁ Magdalena STAŇO KOZUBÍK Kateřina TRIZULJAK Jakub VRZALOVÁ Zuzana RADOVÁ Lenka RÉBLOVÁ Kamila HOLBOVÁ Radka KURUCOVÁ Terézia SVOZILOVÁ Hana ŠTIKA Jiří BLAHÁKOVÁ Ivona DVOŘÁČKOVÁ Barbara PRUDKOVÁ Marie STEHLÍKOVÁ Olga ŠMÍDA Michal KŘEN Leoš SMEJKAL Petr POSPÍŠILOVÁ Šárka DOUBEK Michael

  Article in Periodical

  International Journal of Molecular Sciences, year: 2022, volume: 23, edition: 2, DOI

• Combined drug and CRISPR/CAS9 screening reveals specific targets for SF3B1- and NOTCH1- mutated CLL cells.

  DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika GOTTUMUKKALA Narendra Varma LODHI Yusuf ŠMÍDA Michal

  Conference abstract

  Year: 2022, type: Conference abstract