Project information
The use of biotechnological methods in secondary metabolite production, breeding and micropropagation of medical plant Schizandra chinensis
- Project Identification
- GA521/02/1129
- Project Period
- 1/2002 - 12/2004
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
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Mendel University in Brno
- Responsible person Ing. Helena Vlašínová
- Responsible person RNDr. Eva Kramářová, Ph.D.
The aim of the project is to study potential uses of suspension, callus and embryogenic cultures of medical plant Schizandra chinensis for the production of lignan secondary metabolites; which were found as hepatoprotective, antioxidant, antiviral and anticancer agents. Possibilities of selection of high productive lines and plant production using selected embryogenic cultures will be also studied. The project is based on the use of analytical and isolation methods, developed by specialist teams a the LF MU (Táborská, Slanina), and extraction and cultivation capacity and experience of the team at FF VFU (Kramáoová, Šmejkal). Moreover, embryogenic cultures, developed at the AF MZLU (Vlašínová, Smíšková) will be utilized. The result of the projec will be lignan analysis methods, methodology of lignan production in vitro, and micropropagation methods for selected valuable genotypes.
Publications
Total number of publications: 12
2006
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The effect of polymeric addition on the production of lignans from Schisandra chinensis cell cultures
Future trends in phytochemistry, young scientists symposium, Book of abstracts, year: 2006
2005
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Solid phase extraction followed by high performance liquid chromatography for the determination of bioactive lignans in Schisandra chinensis in vitro cultures
11th international Symposium on Separation sciences, year: 2005
2004
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ANALÝZA LIGNANŮ IN VITRO KULTURY SCHISANDRA CHINENSIS
Chemické listy, year: 2004, volume: 98, edition: 11
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ELICITATION OF SYNTHETIC ABILITIES OF IN VITRO CULTURES SCHIZANDRA CHINENSIS (TURCZ.) BAILL.
Book of Abstracts, XXXIV annual meeting ESNA, year: 2004
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Lignan production in Schisandra chinensis culture in vitro
Aktulne otzky v ekofyziologii rastln, year: 2004
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Lignans in embryogenic culture of Schisandra chinensis
X. Dny rostlinné fyziologie, year: 2004
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Příjem, biologická dostupnost a metabolismus rostlinných polyfenolů u člověka
Chemické listy, year: 2004, volume: 98, edition: 5
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Separation procedures applicable to lignan analysis (review)
Journal of Chromatography B, year: 2004, volume: 812, edition: 1-2
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STANOVENÍ LIGNANŮ SCHISANDRY CHINENSIS POMOCÍ HPLC
Chemické listy, year: 2004, volume: 98, edition: 8
2003
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LIGNANS OF SCHISANDRA CHINENSIS: ANALYSIS IN PLANT CELL CULTURE AND ANTIPROLIFERATIVE ACTIVITY
Year: 2003, number of pages: 1 s.