Project information
Modeling of the structure and interaction of elicitors of the fungus Phytophthora
- Project Identification
- GA522/02/0925
- Project Period
- 1/2002 - 12/2004
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
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Faculty of Science
- prof. RNDr. Vladimír Mikeš, CSc.
Low molecular and oligomeric substances produced by some pathogenic organisms (named elicitors) are recognized by plant by means of specific receptors. These primary interactions regulate signals on the cellular level. Parasitic fungi Phytophthora spp. synthesize a series of homologous proteins able to iniciate hypersensitive reaction and induce acquired non-specific systemic resistance. Moreover, these proteins are sterol carrier proteins. The objective of the project is a modeling of the structure elicitor-sterol complex for a series of mutants obtained by site directed mutagenesis with modified biological efficiency. The elucidation of the role of the sterol-elicitor complex will contribute to development of the new methods of plant protection. The project will be carried out in colaboration with the Laboratory of Phytopharmacie, INRA, Dijon.
Publications
Total number of publications: 10
2009
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Editorial: Protein Design and Engineering for Biocatalysis.
BIOTECHNOLOGY JOURNAL, year: 2009, volume: 2009, edition: 4
2005
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Construction of Cryptogein Mutants, a Proteinaceous Elicitor from Phytophthora, with Altered Abilities To Induce a Defense Reaction in Tobacco Cells
Biochemistry, year: 2005, volume: 44, edition: 17
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Modelování struktury a interakce bílkovinných elicitorů houby Phytophthora
Year: 2005
2004
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Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway
PLANT PHYSIOLOGY AND BIOCHEMISTRY, year: 2004, volume: 2004, edition: 42
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Relationship between secondary structure of elicitins, proteinaceous elicitors of Phytophthora sp. and defense reaction induced in tobacco cells.
Absract Book of 7th Conference of European Foundation for Plant Pathology 2004, year: 2004
2003
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Elicitation of tobacco cells with ergosterol activates a signal pathway including mobilisation of internal calcium
Plant Physiol Biochem, year: 2003, volume: 41, edition: 5
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Role of erogsterol as a signal molecule of fungal-pathogen recognition
HUPO 2nd annaul and IUBMB XIX Congress, Abstracts, year: 2003
2002
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Ergosterol induces mobilization of internal calcium in tobacco cells
Proc. 6th Conf. EFPP, Prague. Plant Protect. Sci, year: 2002
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Lipid elicitors of plant defense reaction
Book of Abstracts of 7th Meeting of WG, year: 2002
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Molecular Mechanism of the interaction of elicitors from Phytophthora with plant cells.
Sborník XVIII Biochemického sjazdu, year: 2002