Project information
CARDIOSTEM
(CARDIOSTEM)
- Project Identification
- 2SGA2744
- Project Period
- 8/2011 - 7/2013
- Investor / Pogramme / Project type
-
South-Moravian Region
- SoMoPro
- Incoming grants
- MU Faculty or unit
-
Faculty of Medicine
- Albano Meli, Ph.D.
Výzkumným cílem tohoto projektu je poskytnout buněčný a molekulární vhled do intracelulárních dějů souvisejicích s vápníkem u získaných a dědičných onemocnění hypertrofickou kardiomyopatií (HCM). Dále se nabízí přáležitost k testování farmaceutických látek na kardiomyocytech specifických pro lidskou HCM.
Publications
Total number of publications: 7
2021
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Cellular pathology of the human heart in Duchenne muscular dystrophy (DMD): lessons learned from in vitro modeling
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, year: 2021, volume: 473, edition: 7, DOI
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Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids
International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 2, DOI
2020
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DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology
Frontiers in bioengineering and biotechnology, year: 2020, volume: 8, edition: June 2019, DOI
2018
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Post-Translational Modifications and Diastolic Calcium Leak Associated to the Novel RyR2-D3638A Mutation Lead to CPVT in Patient-Specific hiPSC-Derived Cardiomyocytes
JOURNAL OF CLINICAL MEDICINE, year: 2018, volume: 7, edition: 11, DOI
2017
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Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing
Year: 2017, type:
2016
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Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing
Biosensors & Bioelectronics, year: 2016, volume: 85, edition: "neuvedeno", DOI
2014
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MicroRNA profiling of activated and tolerogenic human dendritic cells
Mediators of Inflammation, year: 2014, volume: 2014, edition: 259689, DOI