Project information
Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii
- Project Identification
- GBP302/12/G157 (kod CEP: GBP302/12/G157)
- Project Period
- 1/2012 - 12/2018
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Projects to promote excellence in basic research
- MU Faculty or unit
- Faculty of Informatics
- Other MU Faculty/Unit
- Faculty of Medicine
- Cooperating Organization
-
Institute of Biophysics
- Responsible person doc. RNDr. Stanislav Kozubek, DrSc.
- Responsible person doc. RNDr. Dušan Cmarko, Ph.D.
- Responsible person prof. RNDr. Ivan Raška, DrSc.
Projekt excelence navazuje na podobně pojmenovaný úspěěný projekt Centra základního výzkumu LC535 a propojí nejlepší české týmy zabývající se uspořádáním a funkcí jádra buňky a epigenetikou buněk zdravých i nádorových, v normě i při poškození.
Publications
Total number of publications: 122
2013
-
Expression of human BRCA1δ17-19 alternative splicing variant with a truncated BRCT domain inMCF-7 cells results in impaired assembly of DNA repair complexes and aberrant DNA damageresponse
Cellular Signalling, year: 2013, volume: 25, edition: 5, DOI
-
Granulocyte maturation determines ability to release chromatin NETs and loss of DNA damageresponse; these properties are absent in immature AML granulocytes
Biochimica et biophysica acta : Molecular Cell Research, year: 2013, volume: 1833, edition: 3, DOI
-
Hybrid detectors improved time-lapse confocal microscopy of PML and 53BP1 nuclear body co-localization in DNA lesions
Microscopy and Microanalysis, year: 2013, volume: Volume 19, edition: Issue 2, DOI
-
In vitro developmental potential of human embryonic stem cell lines evaluated by gene expression analysis of a new set of differentiation markers
Year: 2013, type: Conference abstract
-
On generating benchmark datasets for evaluation of segmentation and tracking algorithms in fluorescence microscopy
Year: 2013, type:
-
Towards a Realistic Distribution of Cells in Synthetically Generated 3D Cell Populations
17th International Conference on Image Analysis and Processing - ICIAP 2013, year: 2013
-
Use of Human Pluripotent Stem Cells to Derive and Quantify Endothelial Cell-Smooth Muscle Cell Interactions In Vitro
Year: 2013, type: Appeared in Conference without Proceedings
2012
-
Apoptosis in Chronic Myeloid Leukemia Cells Transiently Treated with Imatinib or Dasatinib Is Caused by Residual BCR-ABL Kinase Inhibition
Year: 2012, type: Conference abstract
-
Arrangement of nuclear structures is not transmitted through mitosis but is identical in sister cells
Journal of Cellular Biochemistry, year: 2012, volume: 113, edition: 11, DOI
-
BCR-ABL activity measured by 50% inhibitory concentration for imatinib, p-CrkL/CrkL ratio or p-CrkL ratio in CD34+ cells of patients with chronic myeloid leukemia does not predict treatment response.
Leukemia & lymphoma, year: 2012, volume: 53, edition: 8, DOI