Project information
Endonuleázová a translokázová aktivita v restrikčních-modifikačních komplexech typu I
- Project Identification
- GAP207/12/2323
- Project Period
- 1/2012 - 12/2016
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
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Institute of Microbiology of the ASCR, v. v. i.
Centrum výzkumu globální změny AV ČR, v. v. i.
- Responsible person Daniela Hambergerová
Endonuleázová a translokázová aktivita v restrikčních-modifikačních komplexech typu I.
Publications
Total number of publications: 37
2020
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Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Scientific reports, year: 2020, volume: 10, edition: 1, DOI
2017
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A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
Nucleic Acids Research, year: 2017, volume: 45, edition: 6, DOI
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Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains
Nucleic Acids Research, year: 2017, volume: 45, edition: 1, DOI
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PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis
Molecular Biology of the Cell, year: 2017, volume: 28, edition: 3, DOI
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Role of PCNA and RFC in promoting Mus81-complex activity
BMC BIOLOGY, year: 2017, volume: 15, edition: 90, DOI
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Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci
EMBO Journal, year: 2017, volume: 36, edition: 2, DOI
2016
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A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling
Molecular Cell, year: 2016, volume: 64, edition: 5, DOI
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Cancer TARGETases: DSB Repair as a Pharmacological Target
Pharmacology & Therapeutics, year: 2016, volume: 161, edition: "May", DOI
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DNA, the central molecule of aging
Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis, year: 2016, volume: 786, edition: "April", DOI
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Mitochondrial dysfunction in DDR-related cancer predisposition syndromes
Biochimica et Biophysica Acta - Reviews on Cancer, year: 2016, volume: 1865, edition: 2, DOI