Project information
iNEXT - Infrastructure for NMR, EM and X-ray crystallography for translational research
(iNEXT)
- Project Identification
- 653706
- Project Period
- 9/2015 - 8/2019
- Investor / Pogramme / Project type
-
European Union
- Horizon 2020
- RI Research Infrastructures (Excellent Science)
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Vladimír Sklenář, DrSc.
- Cooperating Organization
-
Universiteit Utrecht
- Responsible person Prof. Rolf Boelens
The iNEXT (infrastructures for NMR, EM and X-ray crystallography for translational research) partnership aims to provide the full range of infrastructures necessary to translate technical excellence and scientific leadership of Structural Biology in Europe to impact modern biomedicine. It will facilitate the development of innovative drugs and biologicals, to meet the major challenges we will face in human and animal health.
Publications
Total number of publications: 9
2023
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Structural basis for different membrane-binding properties of<i> E.</i><i> coli</i> anaerobic and human mitochondrial 8-oxidation trifunctional enzymes
Structure, year: 2023, volume: 31, edition: 7, DOI
2022
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Human myelin proteolipid protein structure and lipid bilayer stacking
Cellular and molecular life sciences, year: 2022, volume: 79, edition: 8, DOI
2019
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In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures Inside Living Xenopus laevis Oocytes
G-QUADRUPLEX NUCLEIC ACIDS: METHODS AND PROTOCOLS, year: 2019, volume: 2035, edition: 2019, DOI
-
In-Cell NMR Spectroscopy of Nucleic Acids in Human Cells
Current Protocols in Nucleic Acid Chemistry, year: 2019, volume: 76, edition: 1, DOI
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Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy
Journal of the American Chemical Society, year: 2019, volume: 141, edition: 34, DOI
2018
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Advances in the cellular structural biology of nucleic acids
FEBS LETTERS, year: 2018, volume: 592, edition: 12, DOI
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Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells
Angewandte Chemie International Edition, year: 2018, volume: 57, edition: 8, DOI
-
Multivalency regulates activity in an intrinsically disordered transcription factor
elife, year: 2018, volume: 7, edition: MAY, DOI
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NMR spectroscopy of nucleic acids in human cells
Year: 2018, type: Conference abstract