Project information
Regulation and manipulation of plant meiosis

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Project Identification
CZ.02.1.01/0.0/0.0/15_003/0000479 (kod CEP: EF15_003/0000479)
Project Period
1/2017 - 10/2022
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
MU Faculty or unit
Central European Institute of Technology

Meiosis lies at the heart of sexual reproduction, the most successful reproductive strategy creating new genetic combinations every generation. This project aims at understanding the mechanisms that define meiotic division and gamete differentiation in plants; part of the effort will be establishing technologies allowing in vitro differentiation of male gametes, live imaging of meiosis and the manipulation of meiotic processes. The approaches will include microfluidics for in vitro cultivation of reproductive tissues coupled with time-laps microscopy (anther on chip technology), next generation sequencing and bioinformatics for identification of new meiotic regulators, CRISPR/Cas9 genome editing and development of techniques for the delivery of biologically active compounds into meiotic. This project well complements ongoing research activities at CEITEC and will strengthen its excellence at multiple levels: 1) It brings unique technology and instrumentation, which will yield important and highly visible discoveries. 2) It combines different expertise and contributes to the multidisciplinarity of the research centre. 3) It has applied potential in plant breeding. 4) It will facilitate establishing close ties to the Vienna Biocenter and promote cross-border collaboration with this prestigious research cluster.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Sustainable Development Goal No.  2 – Zero hunger Sustainable Development Goal No.  3 – Good health and well-being Sustainable Development Goal No.  9 – Industry, innovation and infrastructure

Publications

Total number of publications: 17


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