Project information
Biomarkers for optimization of the treatment of soft - tissue sarcomas
- Project Identification
- NM14
- Project Period
- 1/1998 - 1/2000
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- Molecular Biology Methods Implementation in Diagnosis and Cure
- MU Faculty or unit
- Faculty of Medicine
The project implements the methods of molecular biology to detect the biological properties of soft tissue sarcomas in clinical practice and aims optimize the therapeutic decision-making in individual cases. The biomarkers analyzed for their predictive potential in soft tissue sarkomas include c-myc,PDGF,FGF,Ki67,PCNA,DNA profile,p53,p21,mdm2,bcl-2,Fas,Fasl ligand,ICE p10,apoptosis by TUNEL technique and histoculture drug response assay.
Publications
Total number of publications: 2
2000
-
Biomarkery pro optimalizaci léčby sarkomů měkkých tkání
Year: 2000
-
Sarkomy měkkých tkání- přehled novějších diagnostických a léčebných postupů
Klinická onkologie, year: 2000, volume: 13, edition: 5