Project information
Protein Affinity and Selectivity to Cellular Membranes
- Project Identification
- GA20-20152S
- Project Period
- 1/2020 - 12/2022
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Central European Institute of Technology
The aim of the proposed challenging project is to develop a new method, using which we will
elucidate the relationship between protein sequence and preferred composition and curvature
of human membranes.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 11
2023
-
Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase
Nature Communications, year: 2023, volume: 14, edition: 1, DOI
2022
-
Binding of DEP domain to phospholipid membranes: More than just electrostatics
Biochimica et Biophysica Acta (BBA) - Biomembranes, year: 2022, volume: 1864, edition: 10, DOI
-
Magainin 2 and PGLa in Bacterial Membrane Mimics III: Membrane Fusion and Disruption.
Biophysical Journal, year: 2022, volume: 121, edition: 5, DOI
-
Magainin 2 and PGLa in bacterial membrane mimics IV: Membrane curvature and partitioning
BIOPHYSICAL JOURNAL, year: 2022, volume: 121, edition: 23, DOI
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Synthesis and Profiling of Highly Selective Inhibitors of Methyltransferase DOT1L Based on Carbocyclic C-Nucleosides
Journal of Medicinal Chemistry, year: 2022, volume: 65, edition: 7, DOI
2021
-
Advances in Molecular Understanding of α-helical Membrane-Active Peptides.
Accounts of chemical research, year: 2021, volume: 54, edition: 9, DOI
-
Cardiolipin-Containing Lipid Membranes Attract the Bacterial Cell Division Protein DivIVA
International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 15, DOI
-
Cargo Release from Nonenveloped Viruses and Virus-like Nanoparticles: Capsid Rupture or Pore Formation
ACS Nano, year: 2021, volume: 15, edition: 12, DOI
-
Enhanced translocation of amphiphilic peptides across membranes by transmembrane proteins.
Biophysical Journal, year: 2021, volume: 120, edition: 11, DOI
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Selecting Collective Variables and Free Energy Methods for Peptide Translocation Across Membranes.
Journal of Chemical Information and Modeling, year: 2021, volume: 61, edition: 2, DOI