Project information
Dynamics of proteins interacting with Dishevelled and their importance for Wnt signalling
- Project Identification
- GA204/09/0498
- Project Period
- 1/2009 - 12/2013
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Keywords
- Wnt, Dishevelled, dynamics, tandem affinity purification
- Cooperating Organization
-
University of South Bohemia České Budějovice
- Responsible person Mgr. Lukáš Trantírek, Ph.D.
Publications
Total number of publications: 15
2015
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Fibroblast growth factor and canonical WNT/beta-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage
Biochimica et Biophysica Acta - Molecular Basis of Disease, year: 2015, volume: 1852, edition: 5, DOI
2014
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beta-Arrestin Interacts with the Beta/Gamma Subunits of Trimeric G-Proteins and Dishevelled in the Wnt/Ca2+ Pathway in Xenopus Gastrulation
PLOS ONE, year: 2014, volume: 9, edition: 1, DOI
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beta-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein
Journal of Biological Chemistry, year: 2014, volume: 289, edition: 2, DOI
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Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
FASEB JOURNAL, year: 2014, volume: 28, edition: 5, DOI
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Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1 epsilon and Frizzled5
Journal of Biological Chemistry, year: 2014, volume: 289, edition: 34, DOI
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Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the wnt signaling pathway.
Science Signaling, year: 2014, volume: 7, edition: 317, DOI
2013
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The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling.
PLoS Biology, year: 2013, volume: 2013, edition: 11(5), DOI
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Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
Molecular and cellular biology, year: 2013, volume: 33, edition: 1, DOI
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Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.
Proceedings of the National Academy of Sciences of the United States of America, year: 2013, volume: 110, edition: 7, DOI
2011
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Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P(2) to LRP6 phosphorylation.
The EMBO journal, year: 2011, volume: 30, edition: 8, DOI