Extracellular vesicles (EVs) represent a heterogeneous group of membrane-bounded vesicles released by all cells. Since EVs contain thousands of different cellular proteins and a large number of nucleic acids, which together represent a kind of imprint of the parent cell, a wide range of potential applications is offered. Also, cells undergoing the process of cell death release EVs into their surroundings, which not only affect surrounding and relatively distant cells with different effects but also carry specific information about the type of cell death that is taking place in the dying cells. Given the difficulty of specifically and sensitively detecting different types of cell death in vivo, EVs thus offer a valuable tool to monitor the response of a cell population to therapy using specific molecules.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.