Project information
NCMG: The National Centre for Medical Genomic
(NCMG)
- Project Identification
- LM2023067
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
-
Charles University
- Responsible person prof. Ing. Stanislav Kmoch, CSc.
University Hospital Brno-Bohunice
The National Centre for Medical Genomics (NCMG) is distributed, fully operating infrastructure of five
Czech laboratories developing and performing research in genomic medicine. Their activities include
implementation and adaptation of novel genomic technologies including generation, analysis,
archiving, sharing and displaying sequence data. Other activities are aimed at the exploration of issues
related to the genetic architecture of various diseases, implementation of genomic technologies into
routine diagnostics, and ethical aspects of genomic research and diagnostics.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 14
2024
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CF Day 2023
Year: 2024, type: Popularization text
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Dataset of DNA methylation profiles of 189 pediatric central nervous system, soft tissue, and bone tumors
Data in Brief, year: 2024, volume: 55, edition: August 2024, DOI
-
Del(1p32) is an early and high-risk event in multiple myeloma patients with extraosseous disease
Blood Cancer Journal, year: 2024, volume: 14, edition: 1, DOI
-
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree
Platelets, year: 2024, volume: 35, edition: 1, DOI
-
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression
Molecular Cancer, year: 2024, volume: 23, edition: 1, DOI
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Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome
NPJ PRECISION ONCOLOGY, year: 2024, volume: 8, edition: 1, DOI
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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug
Leukemia, year: 2024, volume: 38, edition: 8, DOI
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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single-cell RNA sequencing
Molecular oncology, year: 2024, volume: 18, edition: 10, DOI
2023
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Application of long-read sequencing in chronic lymphocytic leukemia cases with complex karyotype.
Year: 2023, type: Conference abstract
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Business Research Forum 2023
Year: 2023, type: Popularization text