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Project information
Deciphering the mechanism by which different cytokinin types stimulate cytokinin signalling (Cytokinin types in cytokinin signalling.)

Project Identification
EMBO Short-Term Fellowship Number 7034
Project Period
8/2017 - 10/2017
Investor / Pogramme / Project type
EMBO (European Molecular Biology Organization)
  • Fellowships, grants and career support
MU Faculty or unit
Faculty of Science
Keywords
Arabidopsis; cytokinin; signal perception; two component signalling; root apical meristem

Plants, in contrast to animals, are unique in their developmental plasticity that allows for flexible adaptation to changing environmental conditions. This strategy requires the presence of regulators that mediate specific spatiotemporal changes in particular developmental programs. Phytohormones, especially auxin and cytokinins, have long been known as the principal regulators of plant development (Skoog and Miller, 1957).
The free cytokinin bases N6-isopentenyladenine (iP) and trans-zeatin (tZ) are commonly known to be biologically active compounds. On the other hand, cis-zeatin (cZ) originating from tRNA degradation was previously thought to be inactive but was recently shown to be active (Gajdosova et al., 2011). Our preliminary results provide more evidence for the same. Plant lines lacking tZ or cZ types of cytokinins show opposing phenotypes with regard to root length. This is an indication that different active cytokinin forms have distinct developmental effects - something that has never been shown before. The proposed project will therefore focus on deciphering the mechanism by which cytokinin types influence plant development via stimulation of different signalling pathways.

Publications

Total number of publications: 2

2022

2020

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