Project information
Image analysis in the study of interphase nucleus structure
- Project Identification
- GA202/99/P008
- Project Period
- 1/1999 - 1/2001
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Informatics
The aim of the project is the improvement of current hardware and software for the analysis of images obtained by fluorescence microscopy which is presently used for the study of interphase nucleus structure. The whole system is unique in the world. At p resent time it is already fully automated but requires further hardware as well as software changes. The existing system will be progressively modified and improved so that the research in the field of interphase nucleus structure can be done as fast as possible, as effective as possible and so that the developed equipment remains unique in the world. The optical system will be improved and new methods of optical microscopy will be introduced such as the approach of confocal microscopy with rotating dis k which was the field of proposer's research during his stay at the University of Oxford. The research will be mostly concentrated on the software improvement such as the development of new image analysis algorithms (first of all methods for the segmenta
Publications
Total number of publications: 6
2001
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Combined confocal and wide-field high-resolution cytometry of FISH-stained cells
Cytometry, year: 2001, volume: 45, edition: 1
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FISH Imaging
Confocal and two-photon microscopy: Foundations, applications, and advances, year: 2001, number of pages: 41 s.
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Theoretical versus experimental resolution in optical microscopy
Microscopy research and technique, year: 2001, volume: 53, edition: 2, DOI
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Způsob stanovení vlastností buněk metodou cytometrie s vysokým rozlišením a zařízení pro jeho provádění
Publisher: Úřad průmyslového vlastnictví ČR, state: Czech Republic, patent's number: 288693, year: 2001
2000
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An efficient algorithm for measurement and correction of chromatic aberrations in fluorescence microscopy
Journal of Microscopy, year: 2000, volume: 200, edition: 3
1999
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High-resolution cytometry of FISH dots in interphase cell nuclei
Cytometry, year: 1999, volume: 36, edition: 4