Publication details
Speeding up Mass Spectrometry Imaging with fast Precision Mirror Scanning
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Proceedings |
| Conference | CECE 2012 |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.ce-ce.org/cece2012/Proceedings%20CECE%202012%20Final+late%20abstracts_web.pdf |
| Field | Analytic chemistry |
| Keywords | mass spectrometry imaging; MALDI TOF MSI |
| Description | MALDI mass spectrometry imaging (MALDI MSI) is one of the most rapidly evolving techniques in the field of mass spectrometry. This technique holds a great potential in biomarker discovery, drug distribution analysis and in biosciences generally. Hand in hand with new and more demanding applications a need of new high-throughput instrumentation arises. Though a 1 kHz lasers generation of mass spectrometers brought significant decrease of MSI time, a single high resolution image (10 000 pixels) acquisition can still consume many hours. Here we introduce an incorporation of a high speed scanning mirror redirecting the desorbing laser as a possible way to increase the MSI performance. |
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