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Publication details
Photoremovable Chiral Auxiliary
Authors | |
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Year of publication | 2012 |
Type | Article in Periodical |
Magazine / Source | Photochemical & Photobiological Sciences |
MU Faculty or unit | |
Citation | |
web | http://pubs.rsc.org/en/Content/ArticleLanding/2012/PP/C1PP05096F |
Doi | http://dx.doi.org/10.1039/C1PP05096F |
Field | Organic chemistry |
Keywords | Photochemistry; chiral auxiliary; benzoin; photoremovable protecting group |
Description | A new concept of a photoremovable chiral auxiliary (PCA), based on the chiral benzoin chromophore, is introduced. This moiety can control the asymmetric formation of a Diels-Alder adduct, and then be removed in a subsequent photochemical step in high chemical and quantum yields. Selective formation of the products at up to 96% ee was observed in the presence of a Lewis acid catalyst in the case of a 2-methoxybenzoinyl chiral auxiliary. |
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