Publication details
The Ecm11-Gmc2 Complex Promotes Synaptonemal Complex Formation through Assembly of Transverse Filaments in Budding Yeast
| Authors | |
|---|---|
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | PLOS Genetic |
| MU Faculty or unit | |
| Citation | |
| Doi | https://doi.org/10.1371/journal.pgen.1003194 |
| Field | Genetics and molecular biology |
| Keywords | MEIOTIC CHROMOSOME SYNAPSIS; MEIOSIS-SPECIFIC PROTEIN; DOUBLE-STRAND BREAK; SACCHAROMYCES-CEREVISIAE; ELEMENT PROTEIN; RECOMBINATION; SUMO; SEGREGATION; INITIATION; RED1 |
| Description | Homologous chromosome pairing is one of the crutial step in meiotic division of gametes. Zip1 protein represents a key component during the formation of so-called synaptonemal complex (SC). Analysis of two Zip-related proteins from budding yeast S.cerevisiae revealed that Ecm11 and Gmc2 together with SUMO participate in reguation and correct function of Zip1 during SC assembly. |
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